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. 2023 Oct;49(10):1168-1180.
doi: 10.1007/s00134-023-07180-y. Epub 2023 Aug 24.

Influence of socio-economic status on functional recovery after ARDS caused by SARS-CoV-2: the multicentre, observational RECOVIDS study

Pierre-Louis Declercq  1 , Isabelle Fournel  2   3 , Matthieu Demeyere  4 , Anissa Berraies  5 , Eléa Ksiazek  2   3 , Martine Nyunga  6 , Cédric Daubin  7 , Alexandre Ampere  8 , Bertrand Sauneuf  9 , Julio Badie  10 , Agathe Delbove  11 , Saad Nseir  12   13 , Elise Artaud-Macari  14 , Vanessa Bironneau  15   16 , Michel Ramakers  17 , Julien Maizel  18 , Arnaud-Felix Miailhe  19 , Béatrice Lacombe  20 , Nicolas Delberghe  21 , Walid Oulehri  22 , Hugues Georges  23 , Xavier Tchenio  24 , Caroline Clarot  25 , Elise Redureau  26 , Gaël Bourdin  27 , Laura Federici  28 , Mélanie Adda  29 , David Schnell  30 , Mehdi Bousta  31 , Charlotte Salmon-Gandonnière  32 , Thierry Vanderlinden  33 , Gaëtan Plantefeve  34 , David Delacour  35 , Cyrille Delpierre  36 , Gurvan Le Bouar  37 , Nicholas Sedillot  24 , Gaëtan Beduneau  38 , Antoine Rivière  39 , Nicolas Meunier-Beillard  2   3 , Stéphanie Gélinotte  1 , Jean-Philippe Rigaud  1   40 , Marie Labruyère  41   42   43 , Marjolaine Georges  44 , Christine Binquet  2   3 , Jean-Pierre Quenot  45   46   47 ; RECOVIDS trial investigators, the CRICS-TRIGGERSEP, BOREAL research networks
Collaborators, Affiliations

Influence of socio-economic status on functional recovery after ARDS caused by SARS-CoV-2: the multicentre, observational RECOVIDS study

Pierre-Louis Declercq et al. Intensive Care Med. 2023 Oct.

Erratum in

  • Correction: Influence of socio-economic status on functional recovery after ARDS caused by SARS-CoV-2: the multicentre, observational RECOVIDS study.
    Declercq PL, Fournel I, Demeyere M, Berraies A, Ksiazek E, Nyunga M, Daubin C, Ampere A, Sauneuf B, Badie J, Delbove A, Nseir S, Artaud-Macari E, Bironneau V, Ramakers M, Maizel J, Miailhe AF, Lacombe B, Delberghe N, Oulehri W, Georges H, Tchenio X, Clarot C, Redureau E, Bourdin G, Federici L, Adda M, Schnell D, Bousta M, Salmon-Gandonnière C, Vanderlinden T, Plantefeve G, Delacour D, Delpierre C, Le Bouar G, Sedillot N, Beduneau G, Rivière A, Meunier-Beillard N, Gélinotte S, Rigaud JP, Labruyère M, Georges M, Binquet C, Quenot JP; RECOVIDS trial investigators, the CRICS-TRIGGERSEP, BOREAL research networks. Declercq PL, et al. Intensive Care Med. 2023 Nov;49(11):1438-1439. doi: 10.1007/s00134-023-07217-2. Intensive Care Med. 2023. PMID: 37755457 Free PMC article. No abstract available.

Abstract

Purpose: Survivors after acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19) are at high risk of developing respiratory sequelae and functional impairment. The healthcare crisis caused by the pandemic hit socially disadvantaged populations. We aimed to evaluate the influence of socio-economic status on respiratory sequelae after COVID-19 ARDS.

Methods: We carried out a prospective multicenter study in 30 French intensive care units (ICUs), where ARDS survivors were pre-enrolled if they fulfilled the Berlin ARDS criteria. For patients receiving high flow oxygen therapy, a flow ≥ 50 l/min and an FiO2 ≥ 50% were required for enrollment. Socio-economic deprivation was defined by an EPICES (Evaluation de la Précarité et des Inégalités de santé dans les Centres d'Examens de Santé - Evaluation of Deprivation and Inequalities in Health Examination Centres) score ≥ 30.17 and patients were included if they performed the 6-month evaluation. The primary outcome was respiratory sequelae 6 months after ICU discharge, defined by at least one of the following criteria: forced vital capacity < 80% of theoretical value, diffusing capacity of the lung for carbon monoxide < 80% of theoretical value, oxygen desaturation during a 6-min walk test and fibrotic-like findings on chest computed tomography.

Results: Among 401 analyzable patients, 160 (40%) were socio-economically deprived and 241 (60%) non-deprived; 319 (80%) patients had respiratory sequelae 6 months after ICU discharge (81% vs 78%, deprived vs non-deprived, respectively). No significant effect of socio-economic status was identified on lung sequelae (odds ratio (OR), 1.19 [95% confidence interval (CI), 0.72-1.97]), even after adjustment for age, sex, most invasive respiratory support, obesity, most severe P/F ratio (adjusted OR, 1.02 [95% CI 0.57-1.83]).

Conclusions: In COVID-19 ARDS survivors, socio-economic status had no significant influence on respiratory sequelae 6 months after ICU discharge.

Keywords: ARDS; COVID-19; Deprivation; Respiratory sequelae; Socio-economic.

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Conflict of interest statement

The authors declare no financial or non-financial interests directly or indirectly related to this work.

Figures

Fig. 1
Fig. 1
Flow chart of the study population
See this image and copyright information in PMC

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