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Clinical Trial
. 1979 Jun;25(6):864-9.
doi: 10.1002/cpt1979256864.

Antihypertensive effects of clonidine

M Lilja, A J Jounela, H Juustila, M Marvola
Clinical Trial

Antihypertensive effects of clonidine

M Lilja et al. Clin Pharmacol Ther. 1979 Jun.

Abstract

The antihypertensive effect of clonidine given either two or three times a day with a diuretic was compared in a double-blind crossover study in 18 hypertensive patients. In 11 patients given clonidine three times a day there was better control of blood pressure, although the differences in most instances were of the order of only a few millimeters Hg. There were no differences in the frequency or severity of side effects. Clonidine twice daily with a diuretic appears to be adequate for most patients.

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