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Case Reports
. 2023 Aug 17:50:102535.
doi: 10.1016/j.eucr.2023.102535. eCollection 2023 Sep.

A juxtaglomerular cell tumor revealed by a hemorrhagic stroke. A case report

H Aouini  1 , A Saadi  1 , H Boussaffa  1 , S Zaghbib  1 , M Chakroun  1 , Ben Slama R  1
Affiliations
Case Reports

A juxtaglomerular cell tumor revealed by a hemorrhagic stroke. A case report

H Aouini et al. Urol Case Rep. .

Abstract

With about 110 cases reported in literature, juxtaglomerular cell tumors are rare. We report a 25 years old patient who was admitted in neurology for a hemorrhagic stroke secondary to a cerebral aneurysm rupture due to high blood pressure. Etiological investigations showed a solid mass of the left kidney. A radical nephrectomy was realized and pathological examination and immunohistochemical profile concluded to juxtaglomerular cell tumor. The originality of this observation is based on the mode of presentation of a rare renal tumor by a malignant high blood pressure.

Keywords: Hemorrhagic stroke; High blood pressure; Juxtaglomerular cell tumor; Renal tumor.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Coronal section of CT scan showing a left lower pole renal mass, measuring 65 mm.
Fig. 2
Fig. 2
Macroscopic finding. The tumor is well circumscribed with a yellowish cut surface and hemorrhagic foci.
Fig. 3
Fig. 3
(a) The tumor consists of uniform polygonal cells with eosinophilic cytoplasm and a clear halo around the nucleus (HE x 200). (b) Intense and diffuse expression of CD34 by tumor cells (CD34 x 200).
See this image and copyright information in PMC

References

    1. RoZimmermann Y., Tawadros C., Andrejevic-Blant S., Vogel G. Une cause rare d’hypertension artérielle avec hypokaliémie : un cas de réninome [A rare cause of hypertension with hypokalemia: a case of reninoma] Néphrol Thérapeutique. 2021 Dec;17(7):538–542. doi: 10.1016/j.nephro.2021.05.005. French. - DOI - PubMed
    1. Wong L., Hsu T.H., Perlroth M.G., Hofmann L.V., Haynes C.M., Katznelson L. Reninoma: case report and literature review. J Hypertens. 2008;26(2):368–373. - PubMed
    1. Kuroda N., Gotoda H., Ohe C., et al. Review of juxtaglomerular cell tumor with focus on pathobiological aspect. Diagn Pathol. 2011;6:80. - PMC - PubMed
    1. Marques B., Couto J., Lemos M.C., Rodrigues F. Reninoma: Uma causa rara de Hipertensão endócrina [reninoma: a rare cause of endocrine hypertension] Acta Med Port. 2019 May 8 doi: 10.20344/amp.11660. Portuguese. - DOI - PubMed
    1. Kim J.H., Kim J.H., Cho M.H., et al. Reninoma: a rare cause of curable hypertension. Korean J Pediatr. 2019 Apr;62(4):144–147. - PMC - PubMed

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