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Review
. 2023 Jun 12;9(8):FSO856.
doi: 10.2144/fsoa-2023-0062. eCollection 2023 Sep.

The increasing importance of the oral microbiome in periodontal health and disease

Ruqaiyyah Siddiqui  1   2 , Zahi Badran  3 , Anania Boghossian  1 , Ahmad M Alharbi  4 , Hasan Alfahemi  5 , Naveed Ahmed Khan  6   2
Affiliations
Review

The increasing importance of the oral microbiome in periodontal health and disease

Ruqaiyyah Siddiqui et al. Future Sci OA. .

Abstract

Herein, the aim is to discuss the current knowledge of microbiome and periodontal diseases. Current treatment strategies include mechanical therapy such as root planing, scaling, deep pocket debridement and antimicrobial chemotherapy as an adjuvant therapy. Among promising therapeutic strategies, dental probiotics and oral microbiome transplantation have gained attention, and may be used to treat bacterial imbalances by competing with pathogenic bacteria for nutrients and adhesion surfaces, as well as probiotics targeting the gut microbiome. Development of strategies to prevent and treat periodontal diseases are warranted as both are highly prevalent and can affect human health. Further studies are necessary to better comprehend the microbiome in order to develop innovative preventative measures as well as efficacious therapies against periodontal diseases.

Keywords: gingivitis; oral microbiome; oral microbiome; gut microbiome; periodontal pathogens; periodontitis.

Plain language summary

This paper discusses what we currently know about the microbiome and periodontal diseases. Plaque buildup can happen for various reasons, like eating sugary foods, changes in saliva and the microorganisms in the mouth and gut. To treat periodontal diseases, we currently use antimicrobial medications and scaling. For patients with periodontitis, root planing and deep pocket debridement are used. Dental probiotics are getting attention as a potential treatment option. They work by competing with harmful bacteria for nutrients and surfaces in the mouth, and there are also probiotics that target the gut microbiome.

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Conflict of interest statement

Conflicts of interest disclosure The authors declare that there are no conflicts of interest present.

Figures

Figure 1.
Figure 1.. There is a strong association between periodontal disease and other chronic conditions such as diabetes, heart disease, pregnancy complications, respiratory disease, and so on.
See this image and copyright information in PMC

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