Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Sep;75(3):1441-1446.
doi: 10.1007/s12070-023-03587-7. Epub 2023 Feb 25.

Pharyngocutaneous Fistula in Salvage Laryngectomy: Use of the Stapler Versus Manual Suturing Technique

Affiliations

Pharyngocutaneous Fistula in Salvage Laryngectomy: Use of the Stapler Versus Manual Suturing Technique

Giovanni Salzano et al. Indian J Otolaryngol Head Neck Surg. 2023 Sep.

Abstract

A pharyngocutaneous fistula (PCF) is the most common complication after salvage total laryngectomy (STL) with an incidence ranging from 5 to 73%, causing an increase in morbidity and delaying the patient's recovery. A surgical technique to prevent PCF formation is the use of the stapler to suture the pharyngeal mucosa. We have reviewed the medical files of 91 patients who had undergone STL, dividing the patients into two groups (manual suture vs. stapler), based on the type of pharyngeal suture performed during the STL. We found 12/49 (24.5%) cases of a PCF in group A (manual) and 5/42 (11.9%) cases of a PCF in group B (stapler). There is a statistically significant difference between the two groups with the patients in group B presenting better results in terms of the reduction of the surgical time, the length of the hospital stay and also in the restarting of oral feeding. The advantages of mechanical suturing with the stapler are reduced surgical times, a lower PCF formation rate, which involves an early removal of the nasogastric tube, and reduced hospitalization times. Further studies with a larger case series will be necessary to confirm the results obtained and to standardize the surgical technique.

Keywords: Laryngeal neoplasms; Pharyngocutaneous fistula; Surgical staplers; Total laryngectomy.

PubMed Disclaimer

Conflict of interest statement

Conflict of interestThe authors declare no conflict of interest

Figures

Fig. 1
Fig. 1
View of the mobilized larynx, suspended at the ends by two Allis clamps connected to the pharynx through the mucous membrane
Fig. 2
Fig. 2
Application of the stapler on the pharyngeal mucosa
Fig. 3
Fig. 3
View of the linear suture resulting from the use of the stapler

Similar articles

Cited by

References

    1. Galli J, Salvati A, Di Cintio G, et al. Stapler use in salvage total laryngectomy: a useful tool? Laryngoscope. 2021;131:473–478. doi: 10.1002/lary.28737. - DOI - PubMed
    1. Aires FT, Dedivitis RA, Castro MA, et al. Efficacy of stapler pharyngeal closure after total laryngectomy: a systematic review. Head Neck. 2014;36:739–742. doi: 10.1002/hed.23326. - DOI - PubMed
    1. Liang JW, Li ZD, Li SC, et al. Pharyngocutaneous fistula after total laryngectomy: a systematic review and meta-analysis of risk factors. Auris Nasus Larynx. 2015;42:353–359. doi: 10.1016/j.anl.2015.04.002. - DOI - PubMed
    1. Hasan Z, Dwivedi RC, Gunaratne DA, et al. Systematic review and meta-analysis of the complications of salvage total laryngectomy. Eur J Surg Oncol. 2017;43:42–51. doi: 10.1016/j.ejso.2016.05.017. - DOI - PubMed
    1. Tsetsos N, Poutoglidis A, Vlachtsis K, et al. Twenty-year experience with salvage total laryngectomy: lessons learned. J Laryngol Otol. 2021;135:729–736. doi: 10.1017/S0022215121001687. - DOI - PubMed

LinkOut - more resources