Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 Jul 25;15(7):e42465.
doi: 10.7759/cureus.42465. eCollection 2023 Jul.

Pancreatic Carcinoma Causing Schnitzler's Metastasis

Affiliations
Case Reports

Pancreatic Carcinoma Causing Schnitzler's Metastasis

Laya B Giri et al. Cureus. .

Abstract

Schnitzler's metastasis occurs due to the deposition of the tumor cells in the submucosa of the rectum, leading to rectal stenosis. We present a 60-year-old female who presented with abdominal pain, distension, and vomiting. Abdominal examination showed a distended abdomen and palpable bowel loops, and per rectal examination showed rectal stenosis. Imaging studies suggest rectal stenosis with carcinoma of the pancreas head. The patient was diagnosed with Schnitzler's metastasis with carcinoma of the pancreas head, which has not been reported in the literature. The patient underwent a diversion sigmoid colostomy and was planned for palliative chemotherapy after stenting the common bile duct.

Keywords: carcinoma pancreas; carcinoma stomach; intestinal obstruction; rectal stenosis; schnitzler’s metastasis.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Compute tomography showing (A) circumferential thickening of the rectum (arrow) causing complete obstruction, (B) massively dilated large bowel loops (arrow), (C) dilated common bile duct (red arrow), distended gallbladder (yellow arrow), and pancreatic mass lesion (blue arrow), and (D) intrahepatic biliary radical dilatation (arrow) without any evidence of metastasis.
Figure 2
Figure 2. Magnetic resonance cholangiopancreatography (axial image) showing dilated common bile duct and pancreatic duct (arrow).
Figure 3
Figure 3. Cytological image showing tumor cells showing hyperchromatic pleomorphic nuclei with scant cytoplasm. (A) May Grunwald-Giemsa (MGG) stain and (B) Papanicolaou (PAP) stain.

References

    1. Gastric carcinoma presenting with severe rectal stenosis: ‘schnitzler’s metastasis’: case report and review of the literature. Derici ZS, Sokmen S. Eur Surg. 2016;48:246–249.
    1. Diffuse and intestinal type gastric carcinomas differ in their expression of apoptosis related proteins. van der Woude CJ, Kleibeuker JH, Tiebosch AT, Homan M, Beuving A, Jansen PL, Moshage H. J Clin Pathol. 2003;56:699–702. - PMC - PubMed
    1. Stomach cancer presenting with rectal stenosis: Schnitzler's metastasis. Olano C, De Simone F, Gonzalez F, Gonzalez N, Tchekmedyian A, Pose A, Iade B. Gastrointest Endosc. 2009;70:809–810. - PubMed
    1. Unusual rectal stenosis. Rausei S, Frattini F, Dionigi G, Boni L, Rovera F, Diurni M. J Surg Oncol. 2010;102:713. - PubMed
    1. Laparoscopic low anterior resection for hematogenous rectal metastasis from gastric adenocarcinoma: a case report. Lim SW, Huh JW, Kim YJ, Kim HR. World J Surg Oncol. 2011;9:148. - PMC - PubMed

Publication types

LinkOut - more resources