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Review
. 2023 May 25:22:e00310.
doi: 10.1016/j.parepi.2023.e00310. eCollection 2023 Aug.

Organochlorine knockdown-resistance (kdr) association in housefly (Musca domestica): A systematic review and meta-analysis

Ebrahim Abbasi  1 , Zahra Yazdani  2 , Salman Daliri  3 , Mohammad Djaefar Moemenbellah-Fard  4
Affiliations
Review

Organochlorine knockdown-resistance (kdr) association in housefly (Musca domestica): A systematic review and meta-analysis

Ebrahim Abbasi et al. Parasite Epidemiol Control. .

Abstract

Introduction: Although house flies (Musca domestica) do not directly cause disease in humans, they transmit pathogens to them, which provide the basis for many diseases. The main way to deal with this insect is to use insecticides. Due to the resistance from insecticides, the fight against house flies has been hampered. This study aimed to determine the prevalence of knockdown resistance against organochlorine insecticides in house flies worldwide.

Methods: This study was conducted via a systematic review and meta-analysis to investigate the prevalence of knockdown resistance against organochlorine insecticides in house flies. Accordingly, by searching the databases of Web of Science, PubMed, Scopus, Proquest, Bioone, and Embase, all published articles were extracted, and reviewed until the end of May 2022. Statistical data analysis was performed using the random-effects model in the meta-analysis, meta-regression, and I2 index.

Results: Nine studies entered the meta-analysis process. Based on this, the prevalence of knockdown resistance against organochlorine insecticide in house flies was estimated to be 49.1%. Meta-regression showed that the prevalence of knockdown resistance increased with increasing years of study but decreased with increasing sample size.

Conclusion: According to the findings, about 50% of house flies have knockdown resistance against organochlorine insecticide. As a result, it is necessary to adopt effective and combined methods to combat this insect to control it and prevent the transmission of diseases caused by it.

Keywords: Housefly; Knockdown resistance; Musca domestica; Organochlorine insecticide.

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Conflict of interest statement

None is declared.

Figures

Fig. 1
Fig. 1
The PRISMA flow diagram.
Fig. 2
Fig. 2
Pooled prevalence rate of kdr allele based on a random-effects model.
Fig. 3
Fig. 3
Funnel plot of the kdr allele prevalence.
Fig. 4
Fig. 4
Meta-regression plot of the kdr allele prevalence based on the year of study.
Fig. 5
Fig. 5
Meta-regression plot of the kdr allele prevalence based on the sample size.
See this image and copyright information in PMC

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