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. 2023 Oct 1:251:110940.
doi: 10.1016/j.drugalcdep.2023.110940. Epub 2023 Aug 23.

Racial inequities and addiction research

Affiliations

Racial inequities and addiction research

Wilson M Compton et al. Drug Alcohol Depend. .

Abstract

What accounts for variation across racial and ethnic groups in drug use and harms related to substance use? While explanatory mechanisms for racial and ethnic disparities include differential access to and use of health services, a myriad of other factors, including racism and historical trauma, contribute to drug-related disparities. Furthermore, the addiction scientific workforce, like the full biomedical research enterprise, lacks diversity. This deficit undercuts U.S. scientific leadership and is a major challenge for the field. To address these entrenched problems, the National Institute on Drug Abuse (NIDA) is prioritizing research on health disparities and supporting multiple efforts to enhance scientific workforce diversity. Studies on substance use trends and emerging threats must measure disparities and track progress in reducing disparities, but also acknowledge the limitations of race and ethnicity-based data. Researchers must take the bold step of proposing studies that elucidate causal mechanisms which have the potential to be ameliorated by novel policies and practices. Critically, the impact of racism on all aspects of the substance use trajectory must be assessed to better tailor prevention, harm reduction, treatment, and recovery-support interventions to the specific circumstances of those who need them. Particular attention should be given to people who are incarcerated, who are experiencing homelessness, and who have a history of adverse childhood experiences. Training the next generation of the addiction science workforce needs to address structural barriers to participation with partnerships between funders, such as NIDA, and grantee organizations.

Keywords: Addiction research; Disparities; Racial equity.

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Conflict of interest statement

Declaration of Competing Interest Unrelated to the submitted work, Compton reports ownership of stock in General Electric Co., 3M Co., and Pfizer Inc. Other authors have no conflicts to disclose.

Figures

Figure 1:
Figure 1:
Age-adjusted overdose death rates in the U.S. according to sex, age-group, and racial and ethnic identity before and during the COVID-19 pandemic (from Han et al., 2022).
Figure 2:
Figure 2:
Funding rates for Type 1 R01-equivalent grants submitted to the National Institutes of Health from 2010 to 2022, according to the race and ethnicity of the principal investigator (from Lauer & Bernard, 2023).

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