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. 2023 Nov 1;50(11):e37-e40.
doi: 10.1097/OLQ.0000000000001860. Epub 2023 Aug 24.

Safety of Linezolid During Pregnancy

Affiliations

Safety of Linezolid During Pregnancy

Sabrina Navarro et al. Sex Transm Dis. .

Abstract

With growing maternal and congenital syphilis epidemics and shortages of benzathine penicillin, alternative syphilis treatments are needed. Linezolid has shown efficacy against syphilis in animal models. This review found no teratogenic effects. Some adverse effects were seen in animals, but none were reported in a small number of human studies.

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Conflict of interest statement

Conflicts of interest: none declared.

References

    1. Kojima N, Klausner JD. An update on the global epidemiology of syphilis. Curr Epidemiol Rep 2018; 5:24–38.
    1. Lafond RE, Lukehart SA. Biological basis for syphilis. Clin Microbiol Rev 2006; 19:29–49.
    1. Global health sector strategy on Sexually Transmitted Infections, 2016-2021. Accessed April 17, 2023. https://www.who.int/publications-detail-redirect/WHO-RHR-16.09
    1. Nirappil F, Portnoy J. The tragic, preventable reasons syphilis is surging among U.S. infants. Wash Post . https://www.washingtonpost.com/health/2023/04/01/congenital-syphilis-bab... . Published April 11, 2023. Accessed April 17, 2023.
    1. Sexually Transmitted Disease Surveillance, 2021. Published April 11, 2023. Accessed April 17, 2023. https://www.cdc.gov/std/statistics/2021/default.htm

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