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Clinical Trial
. 2023 Aug 30;23(1):1666.
doi: 10.1186/s12889-023-16569-9.

Socio-economic factors, mood, primary care utilization, and quality of life as predictors of intervention cessation and chronic stress in a type 2 diabetes prevention intervention (PREVIEW Study)

Maija Huttunen-Lenz  1 , Anne Raben  2   3 , Tanja Adam  4 , Ian Macdonald  5   6 , Moira A Taylor  7 , Gareth Stratton  8 , Kelly Mackintosh  9 , J Alfredo Martinez  10   11 , Teodora Handjieva-Darlenska  12 , Georgi Assenov Bogdanov  12 , Sally D Poppitt  13 , Marta P Silvestre  14   15 , Mikael Fogelholm  16 , Elli Jalo  16 , Jennie Brand-Miller  17 , Roslyn Muirhead  17 , Wolfgang Schlicht  18
Affiliations
Clinical Trial

Socio-economic factors, mood, primary care utilization, and quality of life as predictors of intervention cessation and chronic stress in a type 2 diabetes prevention intervention (PREVIEW Study)

Maija Huttunen-Lenz et al. BMC Public Health. .

Abstract

Background: Sedentary lifestyle and unhealthy diet combined with overweight are risk factors for type 2 diabetes (T2D). Lifestyle interventions with weight-loss are effective in T2D-prevention, but unsuccessful completion and chronic stress may hinder efficacy. Determinants of chronic stress and premature cessation at the start of the 3-year PREVIEW study were examined.

Methods: Baseline Quality of Life (QoL), social support, primary care utilization, and mood were examined as predictors of intervention cessation and chronic stress for participants aged 25 to 70 with prediabetes (n = 2,220). Moderating effects of sex and socio-economic status (SES) and independence of predictor variables of BMI were tested.

Results: Participants with children, women, and higher SES quitted intervention earlier than those without children, lower SES, and men. Lower QoL, lack of family support, and primary care utilization were associated with cessation. Lower QoL and higher mood disturbances were associated with chronic stress. Predictor variables were independent (p ≤ .001) from BMI, but moderated by sex and SES.

Conclusions: Policy-based strategy in public health should consider how preventive interventions may better accommodate different individual states and life situations, which could influence intervention completion. Intervention designs should enable in-built flexibility in delivery enabling response to individual needs.

Trial registration: ClinicalTrials.gov Identifier: NCT01777893.

Keywords: Adherence; Diabetes Mellitus; Drop out; Health Behaviors; Lifestyle; Overweight; Prevention; Quality of Life; Stress.

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Conflict of interest statement

Anne Raben has received honorariums from the International Sweeteners Association and Unilever. Pia Siig Vestentoft has received travel grants from the Cambridge Weight Plan, UK. Ian Macdonald was a member of the UK Government Scientific Advisory Committee on Nutrition, Treasurer of the Federation of European Nutrition Societies, Treasurer of the World Obesity Federation, member of the Mars Scientific Advisory Council, member of the Mars Europe Nutrition Advisory Board and Scientific Adviser to the Waltham Centre for Pet Nutrition. He was also a member of the Nestle Research Scientific Advisory Board and of the Novozymes Scientific Advisory Board. Jennie Brand-Miller is President and Director of the Glycemic Index Foundation, oversees a glycaemic index testing service at the University of Sydney and is a co-author of books about diet and diabetes. Sally Poppitt was the Fonterra Chair in Human Nutrition and Principle Investigator for NZ National Science Challenge High Value Nutrition during the PREVIEW intervention. Thomas Meinert Larsen is advisor for the ‘Sense’ diet programme. J. Alfredo Martinez is President of IUNS. All other authors have no conflicts of interest to declare.

Figures

Fig. 1
Fig. 1
PREVIEW Study timeline
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References

    1. Khan MAB, Hashim MJ, King JK, Govender RD, Mustafa H, Al Kaabi J. Epidemiology of Type 2 Diabetes - Global Burden of Disease and Forecasted Trends. J Epidemiol Glob Health. 2020;10(1):107–11. - PMC - PubMed
    1. Tamayo T, Rosenbauer J, Wild SH, Spijkerman AMW, Baan C, Forouhi NG, et al. Diabetes in Europe: an update. Diabetes Res Clin Pract. 2014;103(2):206–217. - PubMed
    1. Lindström J, Neumann A, Sheppard KE, Gilis-Januszewska A, Greaves CJ, Handke U, et al. Take action to prevent diabetes – The IMAGE Toolkit for the Prevention of Type 2 Diabetes in Europe. Horm Metab Res. 2010;42(S 01):S37–55. - PubMed
    1. Wareham NJ, Herman WH. The clinical and public health challenges of diabetes prevention: a search for sustainable solutions. PLoS Med. 2016;13(7):5–7. - PMC - PubMed
    1. Safieddine B, Sperlich S, Beller J, Lange K, Epping J, Tetzlaff J, et al. Socioeconomic inequalities in type 2 diabetes among different population subgroups. Eur J Public Health. 2020;30(5):ckaa165.1044. doi: 10.1093/eurpub/ckaa165.1044. - DOI

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