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. 2023 Aug;28(35):2300423.
doi: 10.2807/1560-7917.ES.2023.28.35.2300423.

Ongoing measles outbreaks in Romania, March 2023 to August 2023

Affiliations

Ongoing measles outbreaks in Romania, March 2023 to August 2023

Mihaela Lazar et al. Euro Surveill. 2023 Aug.

Abstract

Measles cases have recently been increasing in Romania, with 460 confirmed cases by August 2023. From March 2023, measles cases increased, and outbreaks were recorded in Cluj, Bistrita Nasaud, Sibiu and Mures counties. New D8 virus variants were identified, different from the variants detected in Romania before the COVID-19 pandemic. We here provide epidemiological and molecular data on the current increase in measles cases in the context of the measles elimination process in the World Health Organization European Region.

Keywords: MMR; Romania; immunisation; measles; outbreak.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
Possible and confirmed measles cases by month, Romania, October 2022–July 2023 (n = 580)
Figure 2
Figure 2
Age distribution of confirmed measles cases by month, Romania, October 2022–July 2023 (n = 460)
Figure 3
Figure 3
Geographical distribution of confirmed measles cases, Romania, October 2022–July 2023 (n = 460)
Figure 4
Figure 4
Phylogenetic relationship between representative measles strains of genotype D8, Romania, 2023 outbreak, compared with historical sequences (n = 20)

References

    1. European Commission (EC). Commission implementing decision (EU) 2018/945 of 22 June 2018 on the communicable diseases and related special health issues to be covered by epidemiological surveillance as well as relevant case definitions. Brussels: EC; 2018. Available from: https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32018D0945...
    1. Stanescu A, Janta D, Lupulescu E, Necula G, Lazar M, Molnar G, et al. Ongoing measles outbreak in Romania, 2011. Euro Surveill. 2011;16(31):19932. 10.2807/ese.16.31.19932-en - DOI - PubMed
    1. Lazar M, Stănescu A, Penedos AR, Pistol A. Characterisation of measles after the introduction of the combined measles-mumps-rubella (MMR) vaccine in 2004 with focus on the laboratory data, 2016 to 2019 outbreak, Romania. Euro Surveill. 2019;24(29):1900041. 10.2807/1560-7917.ES.2019.24.29.1900041 - DOI - PMC - PubMed
    1. Necula G, Lazar M, Stanescu A, Pistol A, Santibanez S, Mankertz A, et al. Transmission and molecular characterisation of wild measles virus in Romania, 2008 to 2012. Euro Surveill. 2013;18(50):20658. 10.2807/1560-7917.ES2013.18.50.20658 - DOI - PubMed
    1. World Health Organization (WHO). Annex 7.1. Protocol for amplification of measles sequencing window (N-450). Geneva: WHO; 2015. Geneva: WHO; 2022. Available from: https://cdn.who.int/media/docs/default-source/immunization/vpd_surveilla...

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