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. 2023 Sep-Oct;75(5):370-375.
doi: 10.1016/j.ihj.2023.08.004. Epub 2023 Aug 29.

Impact of COVID-19 on heart failure hospitalization and outcome in India - A cardiological society of India study (CSI-HF in COVID 19 times study - "The COVID C-HF study")

Jayagopal P B  1 , Ramakrishnan S  2 , Mohanan P P  3 , Jabir A  4 , Venugopal K  5 , M K Das  6 , Santhosh K  7 , Syam N  8 , J Ezhilan  9 , Rajeev Agarwal  10 , Vaidyanathan P R  11 , Ahmed Hussain Choudhary  12 , Meena C B  13 , Amit Malviya  14 , Arun Gopi  15 , Chopra V K  16 , Stigi Joseph  17 , Krishna Kishore Goyal  18 , John F John  19 , Sandeep Bansal  20 , Harikrishnan S  21 , Praveen Nagula  22 , Johny Joseph  23 , Ajit Bagawat  24 , Sandeep Seth  2 , Urmil Shah  25 , Pravin K Goel  26 , P K Asokan  27 , K K Sethi  28 , Satyavan Sharma  29 , Lt Gen Anup Banerji  30 , Sunandan Sikdar  31 , ManojKumar Agarwala  32 , Sharad Chandra  33 , BishwaBhushan Bharti  34 , S M Ashraf  35 , Smit Srivastava  36 , B Kesavamoorthy  37 , Harinder Kumar Bali  38 , Dipak Sarma  39 , Rajendra Kumar Jain  40 , Sameer I Dani  41 , B H Natesh  42 , Rabindra Nath Chakraborty  43 , Vivek Gupta  44 , Narendra Nath Khanna  44 , Dipankar Mukhopadhyay  45 , Subroto Mandal  46 , Biswajit Majumder  47 , Sridhar L  48 , Meennahalli Palleda Girish  49 , DipakRanjan Das  50 , Tom Devasia  51 , Bhavesh Vajifdar  52 , Tanuj Bhatia  53 , Zia Abdullah  2 , Sanjeev Sharma  54 , Sudeep Kumar  2 , Mathew Lincy  55 , Nitish Naik  4 , Dhiman Kahali  56 , Dhurjati Prasad Sinha  57 , Dipankar Ghosh Dastidar  58 , Gurpreet Sing Wander  59 , Rakesh Yadav  60 , Satyendra Tewari  61 , Suman Bhandari  62 , Pratap Chandra Rath  63 , Vijay Harikisan Bang  64 , Debabrata Roy  65 , ParthoSarathi Banerjee  66 , S Shanmugasundaram  67 , Geevar Zachariah  68
Affiliations

Impact of COVID-19 on heart failure hospitalization and outcome in India - A cardiological society of India study (CSI-HF in COVID 19 times study - "The COVID C-HF study")

Jayagopal P B et al. Indian Heart J. 2023 Sep-Oct.

Abstract

Objectives: The presentation and outcomes of acute decompensated heart failure (ADHF) during COVID times (June 2020 to Dec 2020) were compared with the historical control during the same period in 2019.

Methods: Data of 4806 consecutive patients of acute HF admitted in 22 centres in the country were collected during this period. The admission patterns, aetiology, outcomes, prescription of guideline-directed medical therapy (GDMT) and interventions were analysed in this retrospective study.

Results: Admissions for acute heart failure during the pandemic period in 2020 decreased by 20% compared to the corresponding six-month period in 2019, with numbers dropping from 2675 to 2131. However, no difference in the epidemiology was seen. The mean age of presentation in 2019 was 61.75 (±13.7) years, and 59.97 (±14.6) years in 2020. There was a significant decrease in the mean age of presentation (p = 0.001). Also. the proportion of male patients decreased significantly from 68.67% to 65.84% (p = 0.037). The in-hospital mortality for acute heart failure did not differ significantly between 2019 and 2020 (4.19% and 4.,97%) respectively (p = 0.19). The proportion of patients with HFrEF did not change in 2020 compared to 2019 (76.82% vs 75.74%, respectively). The average duration of hospital stay was 6.5 days.

Conclusion: The outcomes of ADHF patients admitted during the Covid pandemic did not differ significantly. The length of hospital stay remained the same. The study highlighted the sub-optimal use of GDMT, though slightly improving over the last few years.

Keywords: Acute decompensated heart failure; Acute heart failure; COVID-19; GDMT in heart failure.

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Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: ALL PARTICIPATING CENTRE CO INVESTIGATORS reports financial support was provided by Cardiological Society of India.

Figures

Fig. 1
Fig. 1
Monthly trends of Heart failure cases.
Fig. 2
Fig. 2
Comparison of different interventions in 2019 vs 2020.
See this image and copyright information in PMC

References

    1. Bhatt A.S., Moscone A., McElrath E.E., et al. Fewer hospitalizations for acute cardiovascular conditions during the COVID-19 pandemic. J Am Coll Cardiol. 2020 Jul;76(3):280–288. - PMC - PubMed
    1. Zachariah G., Ramakrishnan S., Das M.K., et al. Changing pattern of admissions for acute myocardial infarction in India during the COVID-19 pandemic. Indian Heart J. 2021 Jul;73(4):413–423. - PMC - PubMed
    1. Bhatt A.S., Jering K.S., Vaduganathan M., et al. Clinical Outcomes in Patients With Heart Failure Hospitalized With COVID-19. JACC: Heart Fail. 2021;9(1):65–73. - PMC - PubMed
    1. Goyal P., Reshetnyak E., Khan S., et al. Clinical characteristics and outcomes of adults with a history of heart failure hospitalized for COVID-19. Circ Heart Fail. 2021 Sep;14(9) - PMC - PubMed
    1. Cox Z.L., Lai P., Lindenfeld J. Decreases in acute heart failure hospitalizations during COVID -19. Eur J Heart Fail. 2020 Jun;22(6):1045–1046. - PMC - PubMed