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. 2023 May 12;12(10):1968.
doi: 10.3390/plants12101968.

Chemical Profiling and Antioxidant Activity of Tanacetum vulgare L. Wild-Growing in Latvia

Renāte Šukele  1   2 , Liga Lauberte  3 , Liga Kovalcuka  4 , Konstantins Logviss  3 , Ance Bārzdiņa  1   5 , Agnese Brangule  1   5 , Zoltán Márk Horváth  3 , Dace Bandere  1   5
Affiliations

Chemical Profiling and Antioxidant Activity of Tanacetum vulgare L. Wild-Growing in Latvia

Renāte Šukele et al. Plants (Basel). .

Abstract

The Tanacetum vulgare L. (Tansy) has several ethnobotanical uses, mostly related to the essential oil and sesquiterpene lactones, whereas information regarding other compounds is scarce. This research is designed to characterize the phenolic compounds (flavonoids, phenolic acids, and tannins) to analyze the thujone (which is toxic in high concentrations) content and to detect the antioxidant activity (DPPH assay) of extracts. The main highlights of our work provide a chemical profile of phenolic compounds of T. vulgare harvested from different regions of Latvia, as well as simultaneously support the ethnomedicinal uses for wild T. vulgare through the integration of phenolic compounds as one of the value constituents of leaves and flowers. The extraction yield was 18 to 20% for leaves and 8 to 16% for flowers. The total phenol content in the extracts of T. vulgare as well as their antioxidant activity was different between collection regions and the aerial parts ranging from 134 to 218 mg GAE/g and 32 to 182 mg L-1, respectively. A remarkable variation in the thujone (α + β) content (0.4% up to 6%) was detected in the extracts. T. vulgare leaf extracts were rich in tannins (up to 19%). According to the parameters detected, the extracts of T. vulgare could be considered promising for the development of new herbal products.

Keywords: Tanacetum vulgare; aerial part; antioxidant activity; phenolic compounds; thujone.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Extraction yields of T. vulgare flowers and leaves collected from different places.
Figure 2
Figure 2
Tannin content in the leaf and flower extracts of T. vulgare from different collection places.
Figure 3
Figure 3
LC chromatogram of T. vulgare leaf and flower extracts at 280 nm. QA-quinic acid, GA-gallic acid, CAT-catechin, CGA-chlorogenic acid, CAF-caffeic acid, RUT-rutin, Api-7-O-Glc-apingenin-7-O-glucoside, QRC-quercetin, KAE-kaempherol, API-apingenin.
Figure 4
Figure 4
Radical scavenging activity of leaf and flower extracts (A) and of leaf extracts (B) of T. vulgare harvested from different collection places by DPPH test.
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