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Case Reports
. 2023 Jul;15(Suppl 1):S814-S816.
doi: 10.4103/jpbs.jpbs_44_23. Epub 2023 Jul 5.

Desmoplastic Ameloblastoma-A Case Report

Saranya Manikandan  1 , Gowthaman Vijayakumar  2 , Babu Parthiban  3 , Baskaran Kumarasamy  4
Affiliations
Case Reports

Desmoplastic Ameloblastoma-A Case Report

Saranya Manikandan et al. J Pharm Bioallied Sci. 2023 Jul.

Abstract

Desmoplastic ameloblastoma (DA) is a rare variant of conventional ameloblastoma. It accounts for only 4%-13% of all ameloblastomas. DA was included in the World Health Organization Classification of Head and Neck Tumors (WHO-2005) as a variant of ameloblastoma with specific clinical, imaging, and histological features. The desmoplastic variant of ameloblastoma usually appears in the anterior and premolar regions as a mixed radiolucent and radiopaque lesion, sometimes resembling a benign fibro-osseous lesion.Ameloblastoma is a locally aggressive tumor that may cause recurrence and in rare cases, malignant transformation with repeated postsurgical recurrences. In this paper, we present a case of a 28-year-old female with swelling in the left upper jaw, a biopsy of which turned out to be DA.

Keywords: Ameloblastoma; benign fibro-osseous lesion; desmoplastic ameloblastoma; odontogenic tumor.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
CT imaging showing soap bubble appearance with a displacement of 24 and 25
Figure 2
Figure 2
Odontogenic islands surrounded by abundant thick collagen fibers compressing the odontogenic islands (H and E stain)
Figure 3
Figure 3
Odontogenic epithelium with peripherally arranged cuboidal to few columnar cells with hyperchromatic nuclei and centrally placed squamous cells (H and E stain)
Figure 4
Figure 4
Periphery of the stroma showing osseous metaplasia with active osteoblast rimming (H and E stain)
See this image and copyright information in PMC

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