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Review
. 2023 Aug 16:13:1107703.
doi: 10.3389/fonc.2023.1107703. eCollection 2023.

Particle radiotherapy for breast cancer

Hanguang Ruan  1   2 , Masahiko Okamoto  1   2 , Tatsuya Ohno  1   2 , Yang Li  3 , Yuan Zhou  1   2
Affiliations
Review

Particle radiotherapy for breast cancer

Hanguang Ruan et al. Front Oncol. .

Abstract

Breast cancer is the most common malignant tumor in female patients. Along with surgery, radiotherapy is one of the most commonly prescribed treatments for breast cancer. Over the past few decades, breast cancer radiotherapy technology has significantly improved. Nevertheless, related posttherapy complications should not be overlooked. Common complications include dose-related coronary toxicity, radiation pneumonia, and the risk of second primary cancer of the contralateral breast. Particle radiotherapy with protons or carbon ions is widely attracting interest as a potential competitor to conventional photon radiotherapy because of its superior physical and biological characteristics. This article summarizes the results of clinical research on proton and carbon-ion radiotherapy for treating breast cancer.

Keywords: breast cancer; carbon ion; particle; photon; proton; radiotherapy.

PubMed Disclaimer

Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Schematic diagram of depth-dose distributions of different radiation modalities [LUKAS SCHAUB et al. (18)]
Figure 2
Figure 2
The number of patients with protons and carbon ions beams (collected by the PTCOG, end of 2020).
Figure 3
Figure 3
Computed tomography (CT) dose color wash from an IMRT plan (A) and pencil-beam scanning PT plan (B) [Mutter et al. (13)].
Figure 4
Figure 4
Portal setting and dose distribution of the patients [Karasawa et al. (39)]. Arrow means the deliver beams direction.
See this image and copyright information in PMC

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