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Review
. 2023 Sep 1;8(9):680-689.
doi: 10.1530/EOR-23-0031.

Staphylococcus aureus colonization and periprosthetic joint infection in patients undergoing elective total joint arthroplasty: a narrative review

Michael de Buys  1 , Krisantha Moodley  2 , Josip Nenad Cakic  3 , Jurek R T Pietrzak  1
Affiliations
Review

Staphylococcus aureus colonization and periprosthetic joint infection in patients undergoing elective total joint arthroplasty: a narrative review

Michael de Buys et al. EFORT Open Rev. .

Abstract

Peri-prosthetic joint infections (PJIs) following total joint arthroplasty (TJA) are associated with higher treatment costs, longer hospital admissions and increased morbidity and mortality. Colonization with Staphylococcus aureus is an independent and modifiable risk factor for PJIs and carriers of S. aureus are ten times more likely than non-carriers for post-operative infections. Screening and targeted decolonization, vs universal decolonization without screening, remains a controversial topic. We recommend a tailored approach, based on local epidemiological patterns, resource availability and logistical capacity. Universal decolonization is associated with lower rates of SSI and may reduce treatment costs.

Keywords: Staphylococcus aureus; PJI; arthroplasty; colonization; eradication; infection; staphylococcus.

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Conflict of interest statement

The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported.

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