Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Aug 23:2023:1465957.
doi: 10.1155/2023/1465957. eCollection 2023.

Effectiveness of Cyanoacrylate in the Treatment of Dentin Hypersensitivity: A Systematic Review

Affiliations
Review

Effectiveness of Cyanoacrylate in the Treatment of Dentin Hypersensitivity: A Systematic Review

Adriana da Silva Torres et al. Int J Dent. .

Abstract

Objective: To compare the effectiveness of cyanoacrylate to other treatments or placebo in the management of dentin hypersensitivity (DH).

Materials and methods: The present review was organized based on the preferred reporting items for systematic reviews and meta-analysis (PRISMA) guidelines. The search aimed to answer the following question: is cyanoacrylate effective in the treatment of DH when compared to other treatments or placebo? The following databases were used: PubMed/MEDLINE, Scopus, BVS, Web of Science, Cochrane, Clinicaltrials.gov, Portal Periódicos Capes, Google Scholar, and manual search. The evaluation process started with the information collected from the selected articles according to the Consolidated Standards of Reporting Trials (CONSORT).

Results: Two randomized and five nonrandomized clinical trials were analyzed in the qualitative synthesis. The studies presented different cyanoacrylate formulations, different scales for evaluating pain, and different methods for provoking a painful stimulus. Cyanoacrylate-based products reduce DH in shorter follow-up periods and this reduction persisted throughout the study. The results varied according to the methods used to stimulate the pain. Only two articles showed a low risk of bias and a high level of scientific evidence.

Conclusion: Although there is a limited number of studies in the scientific literature with appropriate methodological quality, the available evidence proves the effectiveness of cyanoacrylate in the treatment of DH. Clinical Relevance. Cyanoacrylate is easy to access, effective, easily applicable, and a low-cost product with satisfactory results.

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
PRISMA flowchart showing the screening of the articles.

References

    1. Holland G. R., Narhi M. N., Addy M., Gangarosa L., Orchardson R. Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. Journal of Clinical Periodontology . 1997;24(11):808–813. doi: 10.1111/j.1600-051X.1997.tb01194.x. - DOI - PubMed
    1. Addy M. Dentine hypersensitivity: new perspectives on an old problem. International Dental Journal . 2002;52(5):367–375. doi: 10.1002/j.1875-595X.2002.tb00936.x. - DOI
    1. Pashley D. H. How can sensitive dentine become hypersensitive and can it be reversed? Journal of Dentistry . 2013;41(S4):S49–S55. doi: 10.1016/S0300-5712(13)70006-X. - DOI - PMC - PubMed
    1. Grippo J. O., Simring M., Schreiner S. Attrition, abrasion, corrosion and abfraction revisited: a new perspective on tooth surface lesions. The Journal of the American Dental Association . 2004;135(8):1109–1118. doi: 10.14219/jada.archive.2004.0369. - DOI - PubMed
    1. Lussi A., Schaffner M. Progression of and risk factors for dental erosion and wedge-shaped defects over a 6-year period. Caries Research . 2000;34(2):182–187. doi: 10.1159/000016587. - DOI - PubMed

LinkOut - more resources