Metastatic melanoma to the proximal ureter

doi:10.1016/j.eucr.2023.102543

Case Reports

. 2023 Aug 24:50:102543.

doi: 10.1016/j.eucr.2023.102543. eCollection 2023 Sep.

Metastatic melanoma to the proximal ureter

Matthew DeSanto¹, Robert Strait¹, Jared Zopp¹, Kevin Brown¹, Samuel Deem¹

Affiliations

PMID: 37664533
PMCID: PMC10474140
DOI: 10.1016/j.eucr.2023.102543

Case Reports

Metastatic melanoma to the proximal ureter

Matthew DeSanto et al. Urol Case Rep. 2023.

. 2023 Aug 24:50:102543.

doi: 10.1016/j.eucr.2023.102543. eCollection 2023 Sep.

Authors

Matthew DeSanto¹, Robert Strait¹, Jared Zopp¹, Kevin Brown¹, Samuel Deem¹

Affiliation

¹ Charleston Area Medical Center, Charleston, West Virgina, USA.

PMID: 37664533
PMCID: PMC10474140
DOI: 10.1016/j.eucr.2023.102543

Abstract

We present an exceptionally rare scenario of obstructive uropathy secondary to a ureteral mass. This case details a 68-year-old female with metastatic stage IIID melanoma of the right heel found to have a two cm right proximal ureteral mass with associated hydronephrosis. Pathology from ureteroscopic biopsy revealed metastatic melanoma to the ureter, creating a unique treatment quandary.

Keywords: Hydronephrosis; Immunotherapy; Metastatic melanoma; Obstructive uropathy.

Published by Elsevier Inc.

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Conflict of interest statement

None.

Figures

**Fig. 1**
Coronal view of a delayed phase CT abdomen pelvis showing right proximal ureteral obstruction secondary to metastatic melanoma.

See this image and copyright information in PMC

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References

1. Eddy K., Chen S. Overcoming immune evasion in melanoma. Int J Mol Sci. 2020;21(23):8984. doi: 10.3390/ijms21238984. Published 2020 Nov 26. - DOI - PMC - PubMed
1. Acikalin A., Bagir E., Karim S., Bisgin A., Izol V., Erdogan S. Primary melanoma of the urinary tract; Clinicopathologic and molecular review of a case series. Pathol Res Pract. 2020;216(9) doi: 10.1016/j.prp.2020.153095. - DOI - PubMed
1. Sandozi A., Jivanji D., Huang Y., Azar O., Schulman A. Robotic distal ureterectomy and reimplant for obstructing metastatic melanoma - surgical considerations in the palliative setting. Can J Urol. 2022;29(5):11323–11325. - PubMed
1. Tseng T.Y., Stoller M.L. Obstructive uropathy. Clin Geriatr Med. 2009;25(3):437–443. doi: 10.1016/j.cger.2009.06.003. - DOI - PubMed
1. Mujoomdar M., Russell E., Dionne F., et al. Optimizing Health System Use of Medical Isotopes and Other Imaging Modalities. Canadian Agency for Drugs and Technologies in Health; Internet. Ottawa (ON): 2012. APPENDIX 2.17, suspected obstructive uropathy.https://www.ncbi.nlm.nih.gov/books/NBK174850/ - PubMed

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[1] Eddy K., Chen S. Overcoming immune evasion in melanoma. Int J Mol Sci. 2020;21(23):8984. doi: 10.3390/ijms21238984. Published 2020 Nov 26. - DOI - PMC - PubMed

[2] Eddy K., Chen S. Overcoming immune evasion in melanoma. Int J Mol Sci. 2020;21(23):8984. doi: 10.3390/ijms21238984. Published 2020 Nov 26. - DOI - PMC - PubMed

[3] Acikalin A., Bagir E., Karim S., Bisgin A., Izol V., Erdogan S. Primary melanoma of the urinary tract; Clinicopathologic and molecular review of a case series. Pathol Res Pract. 2020;216(9) doi: 10.1016/j.prp.2020.153095. - DOI - PubMed

[4] Acikalin A., Bagir E., Karim S., Bisgin A., Izol V., Erdogan S. Primary melanoma of the urinary tract; Clinicopathologic and molecular review of a case series. Pathol Res Pract. 2020;216(9) doi: 10.1016/j.prp.2020.153095. - DOI - PubMed

[5] Sandozi A., Jivanji D., Huang Y., Azar O., Schulman A. Robotic distal ureterectomy and reimplant for obstructing metastatic melanoma - surgical considerations in the palliative setting. Can J Urol. 2022;29(5):11323–11325. - PubMed

[6] Sandozi A., Jivanji D., Huang Y., Azar O., Schulman A. Robotic distal ureterectomy and reimplant for obstructing metastatic melanoma - surgical considerations in the palliative setting. Can J Urol. 2022;29(5):11323–11325. - PubMed

[7] Tseng T.Y., Stoller M.L. Obstructive uropathy. Clin Geriatr Med. 2009;25(3):437–443. doi: 10.1016/j.cger.2009.06.003. - DOI - PubMed

[8] Tseng T.Y., Stoller M.L. Obstructive uropathy. Clin Geriatr Med. 2009;25(3):437–443. doi: 10.1016/j.cger.2009.06.003. - DOI - PubMed

[9] Mujoomdar M., Russell E., Dionne F., et al. Optimizing Health System Use of Medical Isotopes and Other Imaging Modalities. Canadian Agency for Drugs and Technologies in Health; Internet. Ottawa (ON): 2012. APPENDIX 2.17, suspected obstructive uropathy.https://www.ncbi.nlm.nih.gov/books/NBK174850/ - PubMed

[10] Mujoomdar M., Russell E., Dionne F., et al. Optimizing Health System Use of Medical Isotopes and Other Imaging Modalities. Canadian Agency for Drugs and Technologies in Health; Internet. Ottawa (ON): 2012. APPENDIX 2.17, suspected obstructive uropathy.https://www.ncbi.nlm.nih.gov/books/NBK174850/ - PubMed

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Metastatic melanoma to the proximal ureter

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Metastatic melanoma to the proximal ureter

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