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. 2023 Jul 27;31(3):367-373.
doi: 10.5606/tgkdc.dergisi.2023.24088. eCollection 2023 Jul.

Is there a relationship between Haller Index and cardiopulmonary function in children with pectus excavatum?

Ozgur Katrancioglu  1 , Mehmet Ozgel  1 , Feyza Inceoglu  2 , Nurkay Katrancioglu  3 , Ekber Sahin  4
Affiliations

Is there a relationship between Haller Index and cardiopulmonary function in children with pectus excavatum?

Ozgur Katrancioglu et al. Turk Gogus Kalp Damar Cerrahisi Derg. .

Abstract

Background: This study aims to systematically examine the cardiopulmonary functions in children with pectus excavatum and to compare the obtained findings with the Haller Index.

Methods: Between September 2017 and June 2018, medical records of a total of 31 patients (27 males, 4 females; mean age: 14.8±2.0 years; range, 9 to 18 years) with pectus excavatum were retrospectively analyzed. The patients were divided into Group 1 (<2.5), Group 2 (2.5 to 3.19), and Group 3 (>3.2) according to the Haller Index. All groups were systematically evaluated based on pulmonary function tests and echocardiography. Forced vital capacity, forced expiratory volume in 1 second, and the forced expiratory volume in 1 second/ forced vital capacity ratio were calculated. Left ventricular enddiastolic diameter, ejection fraction, mitral valve prolapses, and right ventricular cavity in the apical four-chamber position were evaluated with echocardiography.

Results: Of the patients, 19.4% were in Group 1, 38.7% in Group 2, and 41.9% in Group 3. The mean Haller Index value was 3.09±0.64. According to pulmonary function test results, 16.1% of the patients had restrictive disease and 6.5% had obstructive disease. There was a negative correlation between the index and forced expiratory volume in 1 second and forced vital capacity, and there was a statistically significant decrease in these values, as the Haller Index increased (p<0.017). There was a significant difference in the ejection fraction among the groups (p<0.001) and, as the Haller Index increased, ejection fraction statistically significantly decreased.

Conclusion: Our study results show a negative correlation between the severity of pectus excavatum and pulmonary dysfunction and, as the severity increases, left ventricular function may be affected by the deformity. As a result, there seems to be a significant relationship between the severity of the deformity and cardiopulmonary functions.

Keywords: Pectus excavatum; respiratory function tests; transthoracic echocardiography..

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Conflict of interest statement

Conflict of Interest: The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Figures

Figure 1
Figure 1. FEV1 and HI were found to be strongly negative correlated, and FVC and HI were found to be moderately significantly correlated (p<0.05). FEV1: Forced expiratory volume in 1 second; HI: Haller Index; FVC: Forced vital capacity.
Figure 2
Figure 2. A statistically significant negative correlation was found between ejection fraction and Haller Index (p<0.05).
See this image and copyright information in PMC

References

    1. Brochhausen C, Turial S, Müller FK, Schmitt VH, Coerdt W, Wihlm JM, et al. Pectus excavatum: History, hypotheses and treatment options. Interact Cardiovasc Thorac Surg. 2012;14:801–806. doi: 10.1093/icvts/ivs045. - DOI - PMC - PubMed
    1. Fokin AA, Steuerwald NM, Ahrens WA, Allen KE. Anatomical, histologic, and genetic characteristics of congenital chest wall deformities. Semin Thorac Cardiovasc Surg. 2009;21:44–57. doi: 10.1053/j.semtcvs.2009.03.001. - DOI - PubMed
    1. Coskun ZK, Turgut HB, Demirsoy S, Cansu A. The prevalence and effects of Pectus Excavatum and Pectus Carinatum on the respiratory function in children between 7-14 years old. Indian J Pediatr. 2010;77:1017–1019. doi: 10.1007/s12098-010-0155-5. - DOI - PubMed
    1. Koumbourlis AC, Stolar CJ. Lung growth and function in children and adolescents with idiopathic pectus excavatum. Pediatr Pulmonol. 2004;38:339–343. doi: 10.1002/ppul.20062. - DOI - PubMed
    1. Saleh RS, Finn JP, Fenchel M, Moghadam AN, Krishnam M, Abrazado M, et al. Cardiovascular magnetic resonance in patients with pectus excavatum compared with normal controls. J Cardiovasc Magn Reson. 2010;12:73–73. doi: 10.1186/1532-429X-12-73. - DOI - PMC - PubMed

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