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Comment
. 2023 Sep 4;27(1):342.
doi: 10.1186/s13054-023-04613-4.

Final approval for corticosteroids in severe CAP? For sure, in septic shock

Affiliations
Comment

Final approval for corticosteroids in severe CAP? For sure, in septic shock

Ignacio Martin-Loeches et al. Crit Care. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

IML, BN and AT are authors of the ERS/ESICM/ESCMID/ALAT guidelines for the management of severe community-acquired pneumonia.

Figures

Fig. 1
Fig. 1
Corticosteroids versus control. Outcome: ICU mortality
Fig. 2
Fig. 2
Corticosteroids versus control. Outcome: development of shock
Fig. 3
Fig. 3
Corticosteroids versus control. Outcome: mechanical ventilation-free days
Fig. 4
Fig. 4
Corticosteroids versus control. Outcome: number of patients in mechanical ventilation
Fig. 5
Fig. 5
Corticosteroids versus control. Outcome: hospital infections
Fig. 6
Fig. 6
Corticosteroids versus control. Outcome: gastrointestinal bleeding
Fig. 7
Fig. 7
Corticosteroids versus control. Outcome: cardiac complications

Comment on

References

    1. Vincent JL. Steroids in sepsis: another swing of the pendulum in our clinical trials. Crit Care. 2008;12(2):141. doi: 10.1186/cc6861. - DOI - PMC - PubMed
    1. Torres A, Sibila O, Ferrer M, Polverino E, Menendez R, Mensa J, Gabarrus A, Sellares J, Restrepo MI, Anzueto A, et al. Effect of corticosteroids on treatment failure among hospitalized patients with severe community-acquired pneumonia and high inflammatory response: a randomized clinical trial. JAMA. 2015;313(7):677–686. doi: 10.1001/jama.2015.88. - DOI - PubMed
    1. Villar J, Ferrando C, Martínez D, Ambrós A, Muñoz T, Soler JA, Aguilar G, Alba F, González-Higueras E, Conesa LA, et al. Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial. Lancet Respir Med. 2020;8(3):267–276. doi: 10.1016/S2213-2600(19)30417-5. - DOI - PubMed
    1. Saleem N, Kulkarni A, Snow TAC, Ambler G, Singer M, Arulkumaran N. Effect of corticosteroids on mortality and clinical cure in community-acquired pneumonia: a systematic review, meta-analysis, and meta-regression of randomized control trials. Chest. 2023;163(3):484–497. doi: 10.1016/j.chest.2022.08.2229. - DOI - PubMed
    1. Reyes LF, Rodriguez A, Bastidas A, Parra-Tanoux D, Fuentes YV, García-Gallo E, Moreno G, Ospina-Tascon G, Hernandez G, Silva E, et al. Dexamethasone as risk-factor for ICU-acquired respiratory tract infections in severe COVID-19. J Crit Care. 2022;69:154014. doi: 10.1016/j.jcrc.2022.154014. - DOI - PMC - PubMed

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