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Review
. 2024 Feb;24(2):e202300217.
doi: 10.1002/tcr.202300217. Epub 2023 Sep 5.

Switching it Up: The Promise of Stimuli-Responsive Polymer Systems in Biomedical Science

Yana Shymborska  1   2   3 , Andrzej Budkowski  2 , Joanna Raczkowska  2 , Volodymyr Donchak  1 , Yuriy Melnyk  1 , Viktor Vasiichuk  1 , Yurij Stetsyshyn  1
Affiliations
Review

Switching it Up: The Promise of Stimuli-Responsive Polymer Systems in Biomedical Science

Yana Shymborska et al. Chem Rec. 2024 Feb.

Abstract

Responsive polymer systems have the ability to change properties or behavior in response to external stimuli. The properties of responsive polymer systems can be fine-tuned by adjusting the stimuli, enabling tailored responses for specific applications. These systems have applications in drug delivery, biosensors, tissue engineering, and more, as their ability to adapt and respond to dynamic environments leads to improved performance. However, challenges such as synthesis complexity, sensitivity limitations, and manufacturing issues need to be addressed for successful implementation. In our review, we provide a comprehensive summary on stimuli-responsive polymer systems, delving into the intricacies of their mechanisms and actions. Future developments should focus on precision medicine, multifunctionality, reversibility, bioinspired designs, and integration with advanced technologies, driving the dynamic growth of sensitive polymer systems in biomedical applications.

Keywords: biomedical sciences; biosensors; drug delivery; responsive polymer systems; tissue engineering.

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