Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Jul 31;38(4):e529.
doi: 10.5001/omj.2023.89. eCollection 2023 Jul.

Development and Validation of R-hf Risk Score in Acute Heart Failure Patients in the Middle East

Rajesh Rajan  1 , Mohammed Al Jarallah  1 , Ibrahim Al-Zakwani  2   3 , Raja Dashti  1 , Kadhim Sulaiman  4   5 , Prashanth Panduranga  4   5 , Peter A Brady  6 , Zhanna Kobalava  7
Affiliations

Development and Validation of R-hf Risk Score in Acute Heart Failure Patients in the Middle East

Rajesh Rajan et al. Oman Med J. .

Abstract

Objectives: The Rajan's heart failure (R-hf) score was proposed to aid risk stratification in heart failure patients. The aim of this study was to validate R-hf risk score in patients with acute decompensated heart failure.

Methods: R-hf risk score is derived from the product estimated glomerular filtration rate (mL/min), left ventricular ejection fraction (%), and hemoglobin levels (g/dL) divided by N-terminal pro-brain natriuretic peptide (pg/mL). This was a multinational, multicenter, prospective registry of heart failure from seven countries in the Middle East. Univariable and multivariable logistic regression was applied.

Results: A total of 776 patients (mean age = 62.0±14.0 years, 62.4% males; mean left ventricular ejection fraction = 33.0±14.0%) were included. Of these, 459 (59.1%) presented with acute decompensated chronic heart failure. The R-hf risk score group (≤ 5) was marginally associated with a higher risk of all-cause cumulative mortality at three months (adjusted odds ratio (aOR) = 4.28; 95% CI: 0.90-20.30; p =0.067) and significantly at 12 months (aOR = 3.84; 95% CI: 1.23-12.00; p =0.021) when compared to those with the highest R score group (≥ 50).

Conclusions: Lower R-hf risk scores are associated with increased risk of all-cause cumulative mortality at three and 12 months.

Keywords: Arabia; Chronic Kidney Diseases; Heart Failure; Mortality; Ventricular Dysfunction, Left.

PubMed Disclaimer

References

    1. Schaufelberger M, Swedberg K, Köster M, Rosén M, Rosengren A. Decreasing one-year mortality and hospitalization rates for heart failure in Sweden; Data from the Swedish Hospital Discharge Registry 1988 to 2000. Eur Heart J 2004. Feb;25(4):300-307. 10.1016/j.ehj.2003.12.012 - DOI - PubMed
    1. O’Connor CM, Stough WG, Gallup DS, Hasselblad V, Gheorghiade M. Demographics, clinical characteristics, and outcomes of patients hospitalized for decompensated heart failure: observations from the IMPACT-HF registry. J Card Fail 2005. Apr;11(3):200-205. 10.1016/j.cardfail.2004.08.160 - DOI - PubMed
    1. Sawano M, Shiraishi Y, Kohsaka S, Nagai T, Goda A, Mizuno A, et al. . Performance of the MAGGIC heart failure risk score and its modification with the addition of discharge natriuretic peptides. ESC Heart Fail 2018. Aug;5(4):610-619. 10.1002/ehf2.12278 - DOI - PMC - PubMed
    1. Win S, Hussain I, Hebl VB, Dunlay SM, Redfield MM. Inpatient mortality risk scores and postdischarge events in hospitalized heart failure patients: a community-based study. Circ Heart Fail 2017. Jul;10(7):e003926. 10.1161/CIRCHEARTFAILURE.117.003926 - DOI - PMC - PubMed
    1. Berezin AE, Kremzer AA, Martovitskaya YV, Berezina TA, Samura TA. The utility of biomarker risk prediction score in patients with chronic heart failure. Clin Hypertens 2016. Mar;22(1):3. 10.1186/s40885-016-0041-1 - DOI - PMC - PubMed

LinkOut - more resources