Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Nov 1;208(9):956-963.
doi: 10.1164/rccm.202306-1120PP.

Dysanapsis as a Determinant of Lung Function in Development and Disease

Elizabeth A McGinn  1 , Erica W Mandell  1   2 , Bradford J Smith  1   3   4 , Joseph W Duke  5 , Andrew Bush  6 , Steven H Abman  1   3
Affiliations

Dysanapsis as a Determinant of Lung Function in Development and Disease

Elizabeth A McGinn et al. Am J Respir Crit Care Med. .
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Structural origins of dysanapsis. Created with BioRender.com.
Figure 2.
Figure 2.
Physiologic concepts that may contribute to dysanapsis. Created with BioRender.com.
See this image and copyright information in PMC

Comment in

  • Additional Thoughts on Intrinsic Dysanapsis.
    Tepper RS, Morgan WJ, Taussig LM. Tepper RS, et al. Am J Respir Crit Care Med. 2024 Apr 15;209(8):1040-1041. doi: 10.1164/rccm.202312-2226LE. Am J Respir Crit Care Med. 2024. PMID: 38301264 Free PMC article. No abstract available.

Similar articles

See all similar articles

Cited by

  • Pulmonary function and bronchopulmonary dysplasia classification: insights from the Spanish Registry.
    Ramos-Navarro C, Sánchez-Luna M, Pérez-Tarazona S, Sanz-López E, Maderuelo-Rodriguez E, Rueda-Esteban S, Sánchez-Torres A, Concheiro-Guisán A, Sánchez-Solís M; GEIDIS Research Network. Ramos-Navarro C, et al. Eur J Pediatr. 2024 Sep;183(9):3757-3766. doi: 10.1007/s00431-024-05629-w. Epub 2024 Jun 10. Eur J Pediatr. 2024. PMID: 38858227
  • New spirometry recommendations from the Brazilian Thoracic Association - 2024 update.
    Albuquerque ALP, Berton DC, Campos EVMFÁS, Queiroga-Júnior FJP, Santana ANC, Wong BMS, Batista DR, Melo FX, Didier-Neto FMF, Barros JA, Salge JM, Neder JA, Serra JPC, Voss LR, Fuccio MB, Soares MR, Lima ML, Mendes PRA, Rodrigues-Junior R, Melo SMD, Rodrigues SCS, Lessa T, Pereira CAC, Coutinho HM. Albuquerque ALP, et al. J Bras Pneumol. 2025 Jan 20;50(6):e20240169. doi: 10.36416/1806-3756/e20240169. eCollection 2025. J Bras Pneumol. 2025. PMID: 39841775 Free PMC article.
  • Reply to Tepper et al.: Additional Thoughts on Intrinsic Dysanapsis.
    McGinn EA, Mandell EW, Smith BJ, Duke JW, Bush A, Abman SH. McGinn EA, et al. Am J Respir Crit Care Med. 2024 Apr 15;209(8):1041-1042. doi: 10.1164/rccm.202312-2345LE. Am J Respir Crit Care Med. 2024. PMID: 38301260 Free PMC article. No abstract available.
  • Extending Nasal Continuous Positive Airway Pressure for Preterm Infants: New Targets for an Old Device.
    Kirpalani H, Nelin L, Abman SH. Kirpalani H, et al. Am J Respir Crit Care Med. 2025 Apr;211(4):550-551. doi: 10.1164/rccm.202502-0342ED. Am J Respir Crit Care Med. 2025. PMID: 39998443 Free PMC article. No abstract available.
  • Dysanapsis Genetic Risk Predicts Lung Function Across the Lifespan.
    Debban CL, Ambalavanan A, Ghosh A, Li Z, Buschur KL, Ma Y, George E, Pistenmaa C, Bertoni AG, Oelsner EC, Michos ED, Moraes TJ, Jacobs DR Jr, Christenson S, Bhatt SP, Kaner RJ, Simons E, Turvey SE, Vameghestahbanati M, Engert JC, Kirby M, Bourbeau J, Tan WC, Gabriel SB, Gupta N, Woodruff PG, Subbarao P, Ortega VE, Bleecker ER, Meyers DA, Rich SS, Hoffman EA, Barr RG, Cho MH, Bossé Y, Duan Q, Manichaikul A, Smith BM. Debban CL, et al. Am J Respir Crit Care Med. 2024 Dec 15;210(12):1421-1431. doi: 10.1164/rccm.202401-0011OC. Am J Respir Crit Care Med. 2024. PMID: 38935874
See all "Cited by" articles

References

    1. Green M, Mead J, Turner JM. Variability of maximum expiratory flow-volume curves. J Appl Physiol . 1974;37:67–74. - PubMed
    1. Bush A. COPD: a pediatric disease. COPD . 2008;5:53–67. - PubMed
    1. Narang I, Bush A. Early origins of chronic obstructive pulmonary disease. Semin Fetal Neonatal Med . 2012;17:112–118. - PubMed
    1. Saglani S, Bush A. The early-life origins of asthma. Curr Opin Allergy Clin Immunol . 2007;7:83–90. - PubMed
    1. Gibbons JTD, Wilson AC, Simpson SJ. Predicting lung health trajectories for survivors of preterm birth. Front Pediatr . 2020;8:318. - PMC - PubMed

Publication types

LinkOut - more resources