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Review
. 2024 Aug;479(8):1937-1955.
doi: 10.1007/s11010-023-04825-w. Epub 2023 Sep 8.

A review of immune modulators and immunotherapy in infectious diseases

P Sangeetha Vijayan  1 , Joseph Xavier  1 , Mohanan Parayanthala Valappil  2
Affiliations
Review

A review of immune modulators and immunotherapy in infectious diseases

P Sangeetha Vijayan et al. Mol Cell Biochem. 2024 Aug.

Abstract

The human immune system responds to harmful foreign invaders frequently encountered by the body and employs defense mechanisms to counteract such assaults. Various exogenous and endogenous factors play a prominent role in maintaining the balanced functioning of the immune system, which can result in immune suppression or immune stimulation. With the advent of different immune-modulatory agents, immune responses can be modulated or regulated to control infections and other health effects. Literature provides evidence on various immunomodulators from different sources and their role in modulating immune responses. Due to the limited efficacy of current drugs and the rise in drug resistance, there is a growing need for new therapies for infectious diseases. In this review, we aim to provide a comprehensive overview of different immune-modulating agents and immune therapies specifically focused on viral infectious diseases.

Keywords: Immune modulation; Immune system; Immune therapy; Immunostimulants; Immunosupressants.

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