Leprosy: The age-old companion of humans - Re-evaluation and comparative analysis of Avar-period cases with Hansen's disease from the Danube-Tisza Interfluve, Hungary
- PMID: 37684080
- DOI: 10.1016/j.tube.2023.102393
Leprosy: The age-old companion of humans - Re-evaluation and comparative analysis of Avar-period cases with Hansen's disease from the Danube-Tisza Interfluve, Hungary
Abstract
In recent years, our knowledge of leprosy in the past has substantially been enriched. Nonetheless, much still remains to be discovered, especially in regions and periods from where no written sources are available. To fill in some research gaps, we provide the comparative analysis of eight Avar-period leprosy cases from the Danube-Tisza Interfluve (Hungary). In every case, to reconstruct the biological consequences of leprosy, the detected bony changes were linked with palaeopathological and modern medical information. To reconstruct the social consequences of being affected by leprosy, conceptualisation of the examined individuals' treatment in death was conducted. In every case, the disease resulted in deformation and disfigurement of the involved anatomical areas (rhinomaxillary region, feet, and/or hands) with difficulties in conducting certain physical activities. These would have been disadvantageous for the examined individuals and limited or changed their possibilities to participate in social situations. The most severe cases would have required continuous support from others to survive. Our findings indicate that, despite their very visible disease and associated debility, the examined communities did not segregate leprosy sufferers but provided and cared for them, and maintained a strong enough social network that made their survival possible even after becoming incapable of self-sufficiency.
Keywords: Avar period; Danube-Tisza Interfluve; Leprosy; Macromorphological disease manifestations; Palaeopathology; Social stigma.
Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.
Conflict of interest statement
Declaration of competing interest None.
Similar articles
-
The two extremes of Hansen's disease-Different manifestations of leprosy and their biological consequences in an Avar Age (late 7th century CE) osteoarchaeological series of the Duna-Tisza Interfluve (Kiskundorozsma-Daruhalom-dűlő II, Hungary).PLoS One. 2022 Jun 23;17(6):e0265416. doi: 10.1371/journal.pone.0265416. eCollection 2022. PLoS One. 2022. PMID: 35737690 Free PMC article.
-
A glimpse into the past of Hansen's disease - Re-evaluation and comparative analysis of cases with leprosy from the Avar period of the Trans-Tisza region, Hungary.Tuberculosis (Edinb). 2024 Sep;148:102552. doi: 10.1016/j.tube.2024.102552. Epub 2024 Jul 31. Tuberculosis (Edinb). 2024. PMID: 39142093
-
Life and death of a leprosy sufferer from the 8th-century-CE cemetery of Kiskundorozsma-Kettőshatár I (Duna-Tisza Interfluve, Hungary)-Biological and social consequences of having Hansen's disease in a late Avar Age population from Hungary.PLoS One. 2022 Feb 18;17(2):e0264286. doi: 10.1371/journal.pone.0264286. eCollection 2022. PLoS One. 2022. PMID: 35180265 Free PMC article.
-
Treatment of leprosy/Hansen's disease in the early 21st century.Dermatol Ther. 2009 Nov-Dec;22(6):518-37. doi: 10.1111/j.1529-8019.2009.01274.x. Dermatol Ther. 2009. PMID: 19889136 Review.
-
Hansen's disease (Leprosy): current and future pharmacotherapy and treatment of disease-related immunologic reactions.Pharmacotherapy. 2012 Jan;32(1):27-37. doi: 10.1002/PHAR.1009. Pharmacotherapy. 2012. PMID: 22392826 Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous