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Review
. 2023 Sep 27;12(9):519-521.
doi: 10.1093/jpids/piad066.

A Review of Pediatric Central Line-Associated Bloodstream Infections Reported to the National Healthcare Safety Network: United States, 2016-2022

Christopher Prestel  1 , Lucy Fike  1 , Prachi Patel  1 , Margaret Dudeck  1 , Jonathan Edwards  1 , Ronda Sinkowitz-Cochran  1 , David Kuhar  1
Affiliations
Review

A Review of Pediatric Central Line-Associated Bloodstream Infections Reported to the National Healthcare Safety Network: United States, 2016-2022

Christopher Prestel et al. J Pediatric Infect Dis Soc. .

Abstract

Central line-associated bloodstream infections (CLABSIs) are common healthcare-associated infections in pediatrics. Children's hospital CLABSI standardized infection ratios decreased when comparing 2016-2019 (-26%, 95% CI [-31%, -20%]), and increased from 2019 to 2022 (18%, 95% CI [9%, 26%]). Resilient pediatric CLABSI prevention initiatives are needed.

Keywords: central line-associated bloodstream infection; healthcare-associated infections; infection prevention.

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Conflict of interest statement

Conflict of Interest Disclosures: The authors have no conflicts of interest relevant to this article to disclose.

Figures

Figure 1.
Figure 1.
Graphical representation of the annual distribution of pediatric central line-associated bloodstream infection standardized infection ratios for children’s hospitals for 2016–2022 reported to the National Healthcare Safety Network.
See this image and copyright information in PMC

References

    1. Magill SS, O’Leary E, Janelle SJ, et al.; Emerging Infections Program Hospital Prevalence Survey Team. Emerging infections program hospital prevalence survey team. changes in prevalence of health care-associated infections in U.S. hospitals. N Engl J Med 2018; 379:1732–44. - PMC - PubMed
    1. Centers for Disease Control and Prevention. Antibiotic Resistance and Patient Safety Portal—Central Line-Associated Bloodstream Infections. Accessed January 4, 2023. https://arpsp.cdc.gov/profile/nhsn/clabsi
    1. Dudeck MA, Edwards JR, Allen-Bridson K, et al. National Healthcare Safety Network report, data summary for 2013, device-associated module. Am J Infect Control 2015; 43:206–21. - PMC - PubMed
    1. Patel PR, Weiner-Lastinger LM, Dudeck MA, et al. Impact of COVID-19 pandemic on central-line-associated bloodstream infections during the early months of 2020, National Healthcare Safety Network. Infect Control Hosp Epidemiol 2022; 43:790–3. - PMC - PubMed
    1. Centers for Disease Control and Prevention. The NHSN Standardized Infection Ratio (SIR). Available at: https://www.cdc.gov/nhsn/pdfs/ps-analysis-resources/nhsn-sir-guide.pdf. Accessed 1 May 2023.

MeSH terms