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. 2023 Jul;15(Suppl 2):S1325-S1328.
doi: 10.4103/jpbs.jpbs_102_23. Epub 2023 Apr 28.

A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis

Rakhee  1 , Vivek Kumar  2 , Chintu Kumar Singh  3 , Ananya Arvind  4 , Aasia Ahsan  5 , Sudhanshu Kumar  6 , Debeswar Das  7 , Subham Kumari  8
Affiliations

A Comparative Study of Dexamethasone Ointment along with Triamcinolone Acetonide in Treatment of Recurrent Aphthous Stomatitis

Rakhee et al. J Pharm Bioallied Sci. 2023 Jul.

Abstract

Aim: To assess and compare the efficacy of dexamethasone ointment with triamcinolone acetonide, the gel form, in the treatment of minor recurrent aphthous stomatitis (RAS).

Materials and methods: This was a randomized clinical trial of 60 patients of either sex with clinically diagnosed RAS who were randomly divided into two groups-the dexamethasone ointment group (Group I) and the triamcinolone acetonide gel group (Group II). Patients were asked to apply the gel three times a day on each ulcer. Estimation of the efficacy of gel was done based on the time required for regression in pain, size, and number of ulcers.

Results: The results showed there was a significant difference in size, pain, number, and duration of ulcers in Group I and Group II within 7 days. However, in both groups, no significant difference was noted in the treatment of RAS.

Conclusion: Dexamethasone ointment was found to be efficient in this treatment and was safe as evaluated using clinical assessments.

Keywords: Dexamethasone ointment; recurrent aphthous stomatitis; triamcinolone acetonide.

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Conflict of interest statement

There are no conflicts of interest.

References

    1. Preeti L, Magesh KT, Rajkumar K, Karthik R. Recurrent aphthous stomatitis. J Oral MaxillofacPathol. 2011;15:252–6. - PMC - PubMed
    1. Chalkoo AH, Wani BA, Sharma P, Jan T. Anevaluationof the efficacy of amlexanox and triamcinolone topical paste in the treatment of recurrent aphthousstomatitis. International Journal of Contemporary MEDICAL Research. 2018;5:120–2.
    1. Porter SR, Hegarty A, Kaliakatsou F, Hodgson TA, Scully C. Recurrent aphthous stomatitis. ClinDermatol. 2000;18:569–78. - PubMed
    1. Ship JA. Recurrent aphthous stomatitis. Oral Surg Oral Med Oral Pathol Oral RadiolEndod. 1996;81:141–7. - PubMed
    1. Akintoye SO, Greenberg MS. Recurrent aphthous stomatitis. Dent Clin North Am. 2014;58:281–97. - PMC - PubMed