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. 2023 Jul;15(Suppl 2):S1266-S1269.
doi: 10.4103/jpbs.jpbs_130_23. Epub 2023 Jul 11.

Retinopathy of Prematurity: Incidence and Risk Factor Analysis in Small for Gestational Age Neonates Compared to Appropriate for Gestational Age

Priyanka Arora  1 , Madhushmita Mahapatra  1 , Kamaldeep Arora  2
Affiliations

Retinopathy of Prematurity: Incidence and Risk Factor Analysis in Small for Gestational Age Neonates Compared to Appropriate for Gestational Age

Priyanka Arora et al. J Pharm Bioallied Sci. 2023 Jul.

Abstract

Objective: To analyze the incidence of retinopathy of prematurity (ROP) among preterm neonates who were born small for gestational age (SGA) and appropriate for gestational age (AGA).

Materials and methods: A prospective cohort study among preterm neonates born <34 weeks of gestational age (GA) and <2000 grams birth weight (BW) was conducted. The neonates were divided into AGA and SGA group. Incidence of ROP and risk factors was compared among the groups.

Result: 290 neonates were screened [AGA: 240 (82.8%); SGA: 50 (17.2%)]. The mean birth-weight and gestational age were 1510.7 ± 390.64 grams and 31.4 ± 4.8 weeks, respectively. The incidence of ROP in AGA and SGA was 30.2% and 33%, respectively (P = 0.58), whereas the incidence of type 1 ROP in AGA and SGA was 14% and 19% (P = 0.41). Male sex, anemia, oxygen administration, surfactant administration, sepsis, and PIH were independent significant risk factors for ROP on multivariate analysis.

Conclusion: This study showed that both AGA and SGA premature infants have similar incidence of ROP. SGA is not an independent risk factor for ROP.

Keywords: AGA; ROP; SGA; incidence; newborn.

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Conflict of interest statement

There are no conflicts of interest.

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References

    1. Gergly K, Gerinec A. Retinopathy of prematurity–epidemics, incidence, prevalence, blindness. Bratisl Lek Listy. 2010;111:514–7. - PubMed
    1. Gilbert C, Fielder A, Gordillo L, Quinn G, Semiglia R, Visintin P, et al. Characteristics of infants with severe ROP in countries with low moderate and high levels of development, implications of screening programmes. Pediatrics. 2005;115:e518–25. - PubMed
    1. Holmström G, Tornqvist K, Al-Hawasi A, Nilsson Å, Wallin A, Hellström A. Increased frequency of retinopathy of prematurity over the last decade and significant regional differences. Acta Ophthalmol. 2018;96:142–8. - PubMed
    1. Vanderveen DK, Zupancic JAF. Retinopathy of Prematurity. In: Cloherty JP, Eichenwald EC, Stark AR, editors. Manual of neonatal care. 6th ed. Vol. 2010. Philadelphia, PA: Lippincott Williams and Wilkins; pp. 640–4.
    1. Singh M. Care of the newborn. 7th ed. Vol. 2010. New Delhi: Sagar Publications; Miscellaneous conditions:Retinopathy of prematurity; pp. 425–42.