The providential randomisation of genotypes
- PMID: 37694914
- DOI: 10.1017/S0140525X2200214X
The providential randomisation of genotypes
Abstract
When building causal knowledge in behavioural genetics, the natural randomisation of genotypes at conception (approximately analogous to the artificial randomisation occurring in randomised controlled trials) facilitates the discovery of genetic causes. More importantly, the randomisation of genetic material within families also enables a better identification of (environmental) risk factors and aetiological pathways to diseases and behaviours.
Comment in
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Causal complexity in human research: On the shared challenges of behavior genetics, medical genetics, and environmentally oriented social science.Behav Brain Sci. 2023 Sep 11;46:e206. doi: 10.1017/S0140525X23000833. Behav Brain Sci. 2023. PMID: 37694936
Comment on
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Building causal knowledge in behavior genetics.Behav Brain Sci. 2022 May 5;46:e182. doi: 10.1017/S0140525X22000681. Behav Brain Sci. 2022. PMID: 35510303
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