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Comment
. 2023 Sep 11:46:e212.
doi: 10.1017/S0140525X22002448.

Social scientists would do well to steer clear of polygenic scores

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Comment

Social scientists would do well to steer clear of polygenic scores

David Curtis. Behav Brain Sci. .

Abstract

The problems with polygenic scores (PGSs) have been understated. The fact that they are ancestry-specific means that biases related to sociodemographic factors would be impossible to avoid. Additionally, the requirement to obtain DNA would have profound impacts on study design and required resources, as well as likely introducing recruitment bias. PGSs are unhelpful for social science research.

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