Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2023 Sep 11:46:e215.
doi: 10.1017/S0140525X2200245X.

Taking a lifespan approach to polygenic scores

Affiliations
Comment

Taking a lifespan approach to polygenic scores

Eloise W Freitag et al. Behav Brain Sci. .

Abstract

This commentary is a call to action for researchers to create and use genome-wide association studies (GWASs) with previously missed age groups (e.g., infancy, elderly), which will improve our ability to ask important developmental questions using genetic data to trace pathways across the lifespan.

PubMed Disclaimer

Conflict of interest statement

Competing interest

None.

Comment in

Comment on

References

    1. Bystritsky A, Khalsa SS, Cameron ME, &Schiffman J (2013). Current diagnosis and treatment of anxiety disorders. Pharmacy and Therapeutics, 38(1), 30. - PMC - PubMed
    1. Colombo J, Kannass KN, Jill Shaddy D Kundurthi S, Maikranz JM, Anderson CJ, … Carlson SE (2004). Maternal DHAand the development of attention in infancy and toddlerhood. Child Development, 75(4), 1254–1267. - PubMed
    1. Couto Alves A, De Silva NMG, Karhunen V, Sovio U, Das S, & Taal HR,… Early Growth Genetics (EGG) Consortium (2019). GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI. Science Advances, 5(9), eaaw3095. - PMC - PubMed
    1. Dick DM, Barr PB, Cho SB, Cooke ME, Kuo SIC, Lewis TJ,… Su J (2018). Post-GWAS in psychiatric genetics: A developmental perspective on the “other” next steps. Genes, Brain and Behavior, 17(3), e12447. - PMC - PubMed
    1. Faraone SV, & Larsson H (2019). Genetics of attention deficit hyperactivity disorder. Molecular Psychiatry, 24(4), 562–575. - PMC - PubMed