Taking a lifespan approach to polygenic scores
- PMID: 37694999
- PMCID: PMC10519617
- DOI: 10.1017/S0140525X2200245X
Taking a lifespan approach to polygenic scores
Abstract
This commentary is a call to action for researchers to create and use genome-wide association studies (GWASs) with previously missed age groups (e.g., infancy, elderly), which will improve our ability to ask important developmental questions using genetic data to trace pathways across the lifespan.
Conflict of interest statement
Competing interest
None.
Comment in
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Polygenic scores for social science: Clarification, consensus, and controversy.Behav Brain Sci. 2023 Sep 11;46:e232. doi: 10.1017/S0140525X23000845. Behav Brain Sci. 2023. PMID: 37694994 Free PMC article.
Comment on
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Challenging the utility of polygenic scores for social science: Environmental confounding, downward causation, and unknown biology.Behav Brain Sci. 2022 May 13;46:e207. doi: 10.1017/S0140525X22001145. Behav Brain Sci. 2022. PMID: 35551690 Free PMC article.
References
-
- Colombo J, Kannass KN, Jill Shaddy D Kundurthi S, Maikranz JM, Anderson CJ, … Carlson SE (2004). Maternal DHAand the development of attention in infancy and toddlerhood. Child Development, 75(4), 1254–1267. - PubMed
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