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. 2023 Sep;104(9):001891.
doi: 10.1099/jgv.0.001891.

ICTV Virus Taxonomy Profile: Arenaviridae 2023

Sheli R Radoshitzky  1 , Michael J Buchmeier  2 , Rémi N Charrel  3 , Jean-Paul J Gonzalez  4 , Stephan Günther  5 , Jussi Hepojoki  6   7 , Jens H Kuhn  8 , Igor S Lukashevich  9 , Víctor Romanowski  10 , Maria S Salvato  11 , Manuela Sironi  12 , Mark D Stenglein  13 , Juan Carlos de la Torre  14
Affiliations

ICTV Virus Taxonomy Profile: Arenaviridae 2023

Sheli R Radoshitzky et al. J Gen Virol. 2023 Sep.

Abstract

Arenaviridae is a family for ambisense RNA viruses with genomes of about 10.5 kb that infect mammals, snakes, and fish. The arenavirid genome consists of two or three single-stranded RNA segments and encodes a nucleoprotein (NP), a glycoprotein (GP) and a large (L) protein containing RNA-directed RNA polymerase (RdRP) domains; some arenavirids encode a zinc-binding protein (Z). This is a summary of the International Committee on Taxonomy of Viruses (ICTV) report on the family Arenaviridae, which is available at www.ictv.global/report/arenaviridae.

Keywords: Arenaviridae; ICTV Report; arenavirus; mammarenavirus; reptarenavirus; taxonomy.

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Conflict of interest statement

The authors declare that there are no conflicts of interest.

Figures

Fig. 1.
Fig. 1.
(a) Electron micrograph of lymphocytic choriomeningitis virus budding from an infected cell. (b) Illustration of a particle in (a) showing the spherical and enveloped particle (grey) that is spiked with glycoproteins (GP, gold) around a layer of zinc-binding proteins (Z, brown). The small (S) and large (L) ribonucleoprotein (RNP) complexes inside the particle consist of nucleoprotein (NP; blue) and large (L; green) protein.
Fig. 2.
Fig. 2.
Mammarenavirus genome. The ends of both segments are complementary at their termini, likely promoting the formation of panhandle RNP complexes within the virion. GP, glycoprotein gene; L, large protein gene; NP, nucleoprotein gene; Z, zinc-binding protein gene.
See this image and copyright information in PMC

References

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