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Editorial
. 2023 Aug 31;12(8):2224-2228.
doi: 10.21037/tcr-23-603. Epub 2023 Jul 28.

Dendritic cell vaccination for glioblastoma multiforme patients: has a new milestone been reached?

Stefaan W Van Gool  1 , Jennifer Makalowski  1 , Linde F C Kampers  1 , Peter Van de Vliet  1 , Tobias Sprenger  1 , Volker Schirrmacher  1 , Wilfried Stücker  1
Affiliations
Editorial

Dendritic cell vaccination for glioblastoma multiforme patients: has a new milestone been reached?

Stefaan W Van Gool et al. Transl Cancer Res. .
No abstract available

Keywords: DCVax®-L; Glioblastoma; dendritic cell vaccines (DC vaccines); external control arm (ECA); individualized multimodal immunotherapy (IMI).

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Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://tcr.amegroups.com/article/view/10.21037/tcr-23-603/coif). The authors have no conflicts of interest to declare.

Comment on

  • Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial.
    Liau LM, Ashkan K, Brem S, Campian JL, Trusheim JE, Iwamoto FM, Tran DD, Ansstas G, Cobbs CS, Heth JA, Salacz ME, D'Andre S, Aiken RD, Moshel YA, Nam JY, Pillainayagam CP, Wagner SA, Walter KA, Chaudhary R, Goldlust SA, Lee IY, Bota DA, Elinzano H, Grewal J, Lillehei K, Mikkelsen T, Walbert T, Abram S, Brenner AJ, Ewend MG, Khagi S, Lovick DS, Portnow J, Kim L, Loudon WG, Martinez NL, Thompson RC, Avigan DE, Fink KL, Geoffroy FJ, Giglio P, Gligich O, Krex D, Lindhorst SM, Lutzky J, Meisel HJ, Nadji-Ohl M, Sanchin L, Sloan A, Taylor LP, Wu JK, Dunbar EM, Etame AB, Kesari S, Mathieu D, Piccioni DE, Baskin DS, Lacroix M, May SA, New PZ, Pluard TJ, Toms SA, Tse V, Peak S, Villano JL, Battiste JD, Mulholland PJ, Pearlman ML, Petrecca K, Schulder M, Prins RM, Boynton AL, Bosch ML. Liau LM, et al. JAMA Oncol. 2023 Jan 1;9(1):112-121. doi: 10.1001/jamaoncol.2022.5370. JAMA Oncol. 2023. PMID: 36394838 Free PMC article. Clinical Trial.

References

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    1. Liau LM, Ashkan K, Tran DD, et al. First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma. J Transl Med 2018;16:142. 10.1186/s12967-018-1507-6 - DOI - PMC - PubMed
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