doi: 10.1007/BF01941293.
Immunoquantitation of some cytochrome P-450 isozymes in liver microsomes from streptozotocin-diabetic rats
- PMID: 3770136
- DOI: 10.1007/BF01941293
Item in Clipboard
Immunoquantitation of some cytochrome P-450 isozymes in liver microsomes from streptozotocin-diabetic rats
Experientia.
.
Abstract
Streptozotocin-diabetes in rats leads to a decrease of cytochrome P-450 UT-A (the major form in control rats) and an increase of cytochrome P-450 PB-B (the major one induced by phenobarbital treatment) in liver microsomes. The increased benzphetamine-N-demethylase activity can be related to the induction of cytochrome P-450 PB-B.
Similar articles
-
Interaction of constitutive and phenobarbital-induced cytochrome P-450 isozymes during the sequential oxidation of benzphetamine. Explanation for the difference in benzphetamine-induced hydrogen peroxide production and 455-nm complex formation in microsomes from untreated and phenobarbital-treated rats.Mol Pharmacol. 1983 May;23(3):748-57. Mol Pharmacol. 1983. PMID: 6865917
-
Study of benzphetamine-N-demethylase in streptozotocin-diabetic mice and rats: evidence for the induction of catalytically and immunologically specific forms of cytochrome P450.Biochimie. 1983 Nov-Dec;65(11-12):679-83. doi: 10.1016/s0300-9084(84)80032-2. Biochimie. 1983. PMID: 6201195
-
Metabolism of lidocaine by purified rat liver microsomal cytochrome P-450 isozymes.Biochem Pharmacol. 1989 Dec 15;38(24):4439-44. doi: 10.1016/0006-2952(89)90654-0. Biochem Pharmacol. 1989. PMID: 2604746
-
Cytochrome P450 changes in rats with streptozocin-induced diabetes.Int J Biochem. 1994 Oct-Nov;26(10-11):1261-8. doi: 10.1016/0020-711x(94)90095-7. Int J Biochem. 1994. PMID: 7880321 Review.
-
Sex-specific isozymes of cytochrome P-450.Steroids. 1987 Apr-May;49(4-5):215-45. doi: 10.1016/0039-128x(87)90001-8. Steroids. 1987. PMID: 3331849 Review. No abstract available.