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. 1986 Oct 15;42(10):1163-5.
doi: 10.1007/BF01941294.

Intranuclear crystalloids in arcuate nucleus neurons after clomiphene citrate administration

M Alvarez-Uria, G Gonzalez, A Menendez

Intranuclear crystalloids in arcuate nucleus neurons after clomiphene citrate administration

M Alvarez-Uria et al. Experientia. .

Abstract

The action of high doses of clomiphene citrate on the nuclei of hypothalamic arcuate neurons of male cats has been studied. Clomiphene produces an accumulation of typical crystalloid material in the nuclei. After administration of a protein-synthesis inhibitor, no such material was observed in clomiphene-treated animals. These ultrastructural features could possibly be due to a more intense protein synthesis in the hypothalamic arcuate neurons.

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