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Multicenter Study
. 2024 May;36(5):591-599.
doi: 10.1111/den.14682. Epub 2023 Oct 23.

First report from the International Evaluation of Endoscopic classification Japan NBI Expert Team: International multicenter web trial

Yutaka Saito  1 , Taku Sakamoto  1   2 , Evelien Dekker  3 , Mathieu Pioche  4 , Andreas Probst  5 , Thierry Ponchon  4 , Helmut Messmann  5 , Mario Dinis-Ribeiro  6 , Takahisa Matsuda  1   7 , Hiroaki Ikematsu  8 , Shoichi Saito  9 , Yoshiki Wada  10 , Shiro Oka  11 , Yasushi Sano  12 , Mitsuhiro Fujishiro  13 , Yoshitaka Murakami  7 , Hideki Ishikawa  14 , Haruhiro Inoue  15 , Shinji Tanaka  11   16 , Hisao Tajiri  17 ; IEE‐JNET Group
Collaborators, Affiliations
Multicenter Study

First report from the International Evaluation of Endoscopic classification Japan NBI Expert Team: International multicenter web trial

Yutaka Saito et al. Dig Endosc. 2024 May.

Abstract

Objectives: Narrow-band imaging (NBI) contributes to real-time optical diagnosis and classification of colorectal lesions. The Japan NBI Expert Team (JNET) was introduced in 2011. The aim of this study was to explore the diagnostic accuracy of JNET when applied by European and Japanese endoscopists not familiar with this classification.

Methods: This study was conducted by 36 European Society of Gastrointestinal Endoscopy (ESGE) and 49 Japan Gastroenterological Endoscopy Society (JGES) non-JNET endoscopists using still images of 150 lesions. For each lesion, nonmagnified white-light, nonmagnified NBI, and magnified NBI images were presented. In the magnified NBI, the evaluation area was designated by region of interest (ROI). The endoscopists scored histological prediction for each lesion.

Results: In ESGE members, the sensitivity, specificity, and accuracy were respectively 73.3%, 94.7%, and 93.0% for JNET Type 1; 53.0%, 64.9%, and 62.1% for Type 2A; 43.9%, 67.7%, and 55.1% for Type 2B; and 38.1%, 93.7%, and 85.1% for Type 3. When Type 2B and 3 were considered as one category of cancer, the sensitivity, specificity, and accuracy for differentiating high-grade dysplasia and cancer from the others were 59.9%, 72.5%, and 63.8%, respectively. These trends were the same for JGES endoscopists.

Conclusion: The diagnostic accuracy of the JNET classification was similar between ESGE and JGES and considered to be sufficient for JNET Type 1. On the other hand, the accuracy for Types 2 and 3 is not sufficient; however, JNET 2B lesions should be resected en bloc due to the risk of cancers and JNET 3 can be treated by surgery due to its high specificity.

Keywords: ESGE (European Society of Gastrointestinal Endoscopy); E‐test; JGES (Japan Gastroenterological Endoscopy Society); JNET (Japan NBI Expert Team); narrow‐band imaging (NBI).

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References

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