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. 2023 Sep;28(37):2300471.
doi: 10.2807/1560-7917.ES.2023.28.37.2300471.

Preliminary results on an autochthonous dengue outbreak in Lombardy Region, Italy, August 2023

Irene Cassaniti  1   2   3 , Guglielmo Ferrari  2   3 , Sabrina Senatore  4 , Eva Rossetti  4 , Francesco Defilippo  5 , Manuel Maffeo  6   7 , Luigi Vezzosi  7   8 , Giulia Campanini  3 , Antonella Sarasini  3 , Stefania Paolucci  3 , Antonio Piralla  3 , Davide Lelli  5 , Ana Moreno  5 , Maira Bonini  4 , Marcello Tirani  8   9 , Lorenzo Cerutti  10 , Stefano Paglia  11 , Angelo Regazzetti  12 , Marco Farioli  8 , Antonio Lavazza  5 , Marino Faccini  4 , Francesca Rovida  1   3 , Danilo Cereda  13   8 , Fausto Baldanti  1   13   3 ; Lombardy Dengue network  14 ; Lombardy Dengue Network
Collaborators, Affiliations

Preliminary results on an autochthonous dengue outbreak in Lombardy Region, Italy, August 2023

Irene Cassaniti et al. Euro Surveill. 2023 Sep.

Abstract

In August 2023, six locally acquired dengue virus 1 infections were detected in Lodi province, Lombardy Region, in northern Italy, where the vector Aedes albopictus is present. Four cases were hospitalised, none died. The viruses clustered with Peruvian and Brazilian strains collected between 2021 and 2023. This preliminary report highlights the importance of continued integrated surveillance of imported vector-borne virus infections and the potential for tropical disease outbreaks in highly populated regions of northern Italy where competent vectors are present.

Keywords: Dengue; Italy; autochthonous cases; phylogenetic analysis; serology; virus.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure
Figure
Phylogenetic tree of dengue virus serotype 1 complete genome sequences, Italy, August 2023 (n = 5 samples from the current outbreak)
See this image and copyright information in PMC

References

    1. Bhatt S, Gething PW, Brady OJ, Messina JP, Farlow AW, Moyes CL, et al. The global distribution and burden of dengue. Nature. 2013;496(7446):504-7. 10.1038/nature12060 - DOI - PMC - PubMed
    1. Wilder-Smith A, Ooi EE, Horstick O, Wills B. Dengue. Lancet. 2019;393(10169):350-63. 10.1016/S0140-6736(18)32560-1 - DOI - PubMed
    1. La Ruche G, Souarès Y, Armengaud A, Peloux-Petiot F, Delaunay P, Desprès P, et al. First two autochthonous dengue virus infections in metropolitan France, September 2010. Euro Surveill. 2010;15(39):19676. 10.2807/ese.15.39.19676-en - DOI - PubMed
    1. Gjenero-Margan I, Aleraj B, Krajcar D, Lesnikar V, Klobučar A, Pem-Novosel I, et al. Autochthonous dengue fever in Croatia, August-September 2010. Euro Surveill. 2011;16(9):19805. 10.2807/ese.16.09.19805-en - DOI - PubMed
    1. Alves MJ, Fernandes PL, Amaro F, Osório H, Luz T, Parreira P, et al. Clinical presentation and laboratory findings for the first autochthonous cases of dengue fever in Madeira Island, Portugal, October 2012. Euro Surveill. 2013;18(6):20398. 10.2807/ese.18.06.20398-en - DOI - PubMed

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