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Review
. 2023 Oct;20(10):e202301008.
doi: 10.1002/cbdv.202301008. Epub 2023 Oct 5.

Aptamers: Features, Synthesis and Applications

Aiswarya P U  1 , Gopika Raj  1 , Jinju John  1 , Malavika Mohan K  1 , Franklin John  1 , Jinu George  1
Affiliations
Review

Aptamers: Features, Synthesis and Applications

Aiswarya P U et al. Chem Biodivers. 2023 Oct.

Abstract

Aptamers have become a topic of interest among the researchers and scientists since they not only possess all of the benefits of antibodies but also possess special qualities including heat stability, low cost, and limitless uses⋅ Here we give a review about the features, applications, and challenges of aptamers and also how they are beneficial over the antibodies for biomedical applications. Their unique features make aptamers a prominent tool in therapeutics, diagnostics, biosensors and targeted drug delivery. In conclusion, aptamers represent exciting materials for a variety of applications and can be modified to improve their properties and to extend their applications in biomedical field.

Keywords: SELEX; aptamers; diagnosis; sensors; targeted drug delivery; therapeutics.

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