Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Jun 28;279(5716):778-81.
doi: 10.1038/279778a0.

Cloned fragments of the plasmid ColV,I-K94 specifying virulence and serum resistance

M M Binns, D L Davies, K G Hardy

Cloned fragments of the plasmid ColV,I-K94 specifying virulence and serum resistance

M M Binns et al. Nature. .

Abstract

A cloned BamH1-generated fragment of ColV,I-K94 increased the virulence of Escherichia coli, causing an approximately 100-fold reduction in LD50 for chicks. A genetic determinant for resistance to the bactericidal effects of serum was mapped to a 5,300 base-pair sequence within the fragment. Neither colicin V nor immunity to colicin V affected the pathogenicity of E. coli for chicks.

PubMed Disclaimer

LinkOut - more resources