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. 2023 Oct;58(5):511-518.
doi: 10.1177/00185787231169458. Epub 2023 May 3.

Antiemetics and Apfel Scores in Orthopedic Surgery

Van N Tran  1 , Brennan J Fitzpatrick  1 , Sourav Das  1   2
Affiliations

Antiemetics and Apfel Scores in Orthopedic Surgery

Van N Tran et al. Hosp Pharm. 2023 Oct.

Abstract

Background: Postoperative nausea and vomiting (PONV) is a common complication following surgery. Only a few risk factors have consistently been reported to be independent predictors for PONV.

Aim: To report Apfel scores for orthopedic patients then correlate these scores to the number of antiemetics prescribed and subsequently administered in both the perioperative and post operative setting and determine if screening for Apfel scores is beneficial to predict PONV.

Methods: A retrospective analysis of patients admitted under orthopedic units between 1st July 2020 and 31st July 2020 was conducted at a tertiary teaching hospital in Australia. Patients were screened and allocated an Apfel score and antiemetics agents prescribed and subsequently administered were recorded.

Results: A total of 115 patients were screened for inclusion. Of these 4 patients met this exclusion criteria, resulting in a total sample size of 111 patients. An Apfel score of 2 was reported in 45.0% of patients, followed by 28.8% of patients scoring 3, with 12.6% scoring one. Only 5.4% of patients scored the highest risk of 4, with 8.2% of patients with no Apfel score documented.

Conclusion: Orthopedic patients tend to score 2 or more in their Apfel score placing them at higher risk of postoperative nausea and/or vomiting according to the collectively validated Apfel's simplified risk score. There was no statistically significant relationship between the Apfel score and the number of antiemetic agents prescribed or administered from both the perioperative and post-operative setting following orthopedic surgery in this cohort of adult patients.

Keywords: Apfel score; antiemetic agents; orthopedics; perioperative medicine; post-operative nausea and vomiting.

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Conflict of interest statement

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Bar plots show the distribution of number of antiemetic agents versus Apfel Score.
Figure 2.
Figure 2.
Number of agents administered peri-operatively (prophylaxis).
Figure 3.
Figure 3.
Number of antiemetic prescribed for PACU.
Figure 4.
Figure 4.
Number of antiemetic administered in PACU.
See this image and copyright information in PMC

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