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Comment
. 2023 Dec;98(12):E356.
doi: 10.1002/ajh.27083. Epub 2023 Sep 15.

Chronic GvHD in a prognostic model: Graft versus leukemia predictor or immortal time bias?

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Chronic GvHD in a prognostic model: Graft versus leukemia predictor or immortal time bias?

Erik G J von Asmuth et al. Am J Hematol. 2023 Dec.
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  • Impact of a novel prognostic model on allogeneic hematopoietic stem cell transplantation outcomes in patients with CMML.
    Zhou JY, Wang S, Yuan HL, Xu YJ, Huang XB, Gao SJ, Zhang YC, Zhou F, Liu Y, Song XM, Cai Y, Liu XL, Luo Y, Yang LX, Yang JM, Wang LB, Li YH, Huang R, Wang SQ, Zhou M, Dong YJ, Wang Q, Zhang X, Feng YM, Du X, Ling W, Zhu H, Zhu ZM, Chen XL, Wang SY, Meng FK, Bi KH, Huang N, Jiang M, Niu T, Ji J, Wan DM, Bian ZL, Chen Y, Liu L, Yan XQ, Yang X, Yi H, Wei XD, Li X, Cheng Q, Yuan CL, Wang W, Zhou YH, Ye BD, Ding J, Wu YJ, Huang QS, Zhu XL, Chen YH, He Y, Wang FR, Zhang YY, Mo XD, Han W, Wang JZ, Wang Y, Chen H, Zhao XY, Chang YJ, Liu KY, Huang XJ, Zhang XH. Zhou JY, et al. Am J Hematol. 2023 Sep;98(9):1394-1406. doi: 10.1002/ajh.26999. Epub 2023 Jun 27. Am J Hematol. 2023. PMID: 37366294

References

REFERENCES

    1. Zhou JY, Wang S, Yuan HL, et al. Impact of a novel prognostic model on allogeneic hematopoietic stem cell transplantation outcomes in patients with CMML. Am J Hematol. 2023;98:1394-1406.
    1. Yadav K, Lewis RJ. Immortal time bias in observational studies. JAMA. 2021;325(7):686-687.
    1. Itonaga H, Iwanaga M, Aoki K, et al. Impacts of graft-versus-host disease on outcomes after allogeneic hematopoietic stem cell transplantation for chronic myelomonocytic leukemia: a nationwide retrospective study. Leuk Res. 2016;41:48-55.
    1. Beyersmann J, Gastmeier P, Wolkewitz M, Schumacher M. An easy mathematical proof showed that time-dependent bias inevitably leads to biased effect estimation. J Clin Epidemiol. 2008;61(12):1216-1221.

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