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Case Reports
. 2023 Sep 15;102(37):e35232.
doi: 10.1097/MD.0000000000035232.

Pulmonary mucosa-associated lymphoid tissue lymphoma with Sjögren's syndrome and literature review: A case report

Limin Yang  1 , Rongfeng Qu, Fang Liu, Chunmei Hu
Affiliations
Case Reports

Pulmonary mucosa-associated lymphoid tissue lymphoma with Sjögren's syndrome and literature review: A case report

Limin Yang et al. Medicine (Baltimore). .

Abstract

Introduction: A 54-year-old woman was admitted to hospital with chest tightness, shortness of breath, and chest pain on exertion. Her chest computed tomography showed a space-occupying lesion in the right lower lobe of the lung.

Case presentation: The ultrasound-guided right lung mass biopsy showed mucosa-associated lymphoid tissue (MALT), and the patient was diagnosed with Sjögren's syndrome (SS). The patient's symptoms were partially relieved with chemotherapy.

Conclusions: Autoimmune diseases like SS and systemic lupus erythematosus are recognized risk factors for pulmonary MALT. It is necessary to identify predictors of malignant transformation of SS to pulmonary MALT lymphoma.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Figure 1.
Figure 1.
Histological findings for right lung mass with hematoxy-in and eosin staining (original magnification, ×4, ×400) and immunostaining at diagnosis of MALT. Immunohistochemically, abnormal lymphocytes are positive for CD79, CD138, and κ and negative for CD20.
Figure 2.
Figure 2.
Computed tomography scan shows that the soft tissue density mass in the lower lobe of the right lung was flaky and had a slight high-density shadow. (A) Before treatment and (B) after treatment.
See this image and copyright information in PMC

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