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. 2023 Oct 5;30(10):1283-1284.
doi: 10.1016/j.stem.2023.08.012. Epub 2023 Sep 14.

Cis-regulatory arbitrators of regeneration

Piotr Konieczny  1 , Shruti Naik  2
Affiliations
Free article

Cis-regulatory arbitrators of regeneration

Piotr Konieczny et al. Cell Stem Cell. .
Free article

Abstract

Mammals favor healing with scaring over functional tissue regeneration.1 In this issue of Cell Stem Cell, Mack et al. use "super-healer" mice to identify cis-regulatory variations that direct regenerative versus fibrotic gene expression in wound fibroblasts and they uncover complement factor H as a molecular driver of skin regeneration.2.

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Conflict of interest statement

Declaration of interests S.N. is on the scientific advisory board of Seed Inc. and receives funding from Takeda Pharmaceuticals.

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