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Review
. 2024 Nov;19(8):1189-1194.
doi: 10.1177/15589447231196902. Epub 2023 Sep 16.

The Role of Surgery in the Management of Radiation-Induced Brachial Plexopathy

Affiliations
Review

The Role of Surgery in the Management of Radiation-Induced Brachial Plexopathy

Mira Shoukry et al. Hand (N Y). 2024 Nov.

Abstract

Radiation-induced brachial plexopathy (RIBP) is a rare long-term complication of radiation therapy often causing pain, motor deficit, and overall quality of life reduction for affected patients. While a standard treatment for RIBP is yet to be established, management consists mostly of symptom management through the use of medications and physical therapy. There is a lack of evidence regarding the efficacy of surgical treatment. Omentoplasties and other vascularized flaps are commonly discussed options for eliminating neuropathic pain associated with RIBP. However, these approaches show no meaningful improvement in motor function. While limited, current literature suggests that nerve transfers may be an option for relief of neuropathic pain as well as restoration of motor function. This review of literature explores the options available to those affected by RIBP with a focus on the role of surgery.

Keywords: brachial plexus; diagnosis; nerve; nerve transfer; omentoplasty; radiation-induced brachial plexopathy; specialty; surgery.

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Conflict of interest statement

Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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References

    1. Schierle C, Winograd JM. Radiation-induced brachial plexopathy: review. Complication without a cure. J Reconstr Microsurg. 2004;20(2):149-152. doi:10.1055/s-2004-820771. - DOI - PubMed
    1. Azzam P, Mroueh M, Francis M, et al.. Radiation-induced neuropathies in head and neck cancer: prevention and treatment modalities. Ecancermedicalscience. 2020;14:1133. doi:10.3332/ecancer.2020.1133. - DOI - PMC - PubMed
    1. Stoll BA, Andrews JT. Radiation-induced peripheral neuropathy. BMJ. 1966;1(5491):834-837. doi:10.1136/bmj.1.5491.834. - DOI - PMC - PubMed
    1. Mondrup K, Olsen NK, Pfeiffer P, et al.. Clinical and electrodiagnostic findings in breast cancer patients with radiation-induced brachial plexus neuropathy. Acta Neurol Scand. 1990;81(2):153-158. doi:10.1111/j.1600-0404.1990.tb00952.x. - DOI - PubMed
    1. Delanian S, Lefaix JL. The radiation-induced fibroatrophic process: therapeutic perspective via the antioxidant pathway. Radiother Oncol. 2004;73(2):119-131. doi:10.1016/j.radonc.2004.08.021. - DOI - PubMed

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