Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Sep 12:16:100472.
doi: 10.1016/j.resplu.2023.100472. eCollection 2023 Dec.

Cardiac Arrest Bundle of cARE Trial (CABARET) survey of current UK neuroprotective CPR practice

Affiliations

Cardiac Arrest Bundle of cARE Trial (CABARET) survey of current UK neuroprotective CPR practice

James Raitt et al. Resusc Plus. .

Abstract

Despite low out of hospital cardiac arrest (OOHCA) survival rates within the UK, animal studies hint at improved cerebral blood flow via a bundled neuroprotective CPR approach. The CABARET study introduces three key devices: the Head Up Position (HUP), Active Compression/Decompression (ACD) CPR, and the Impedance Threshold Device (ITD). A survey involving 27 UK pre-hospital critical care services indicated none are using these interventions widely, either alone or bundled. The CABARET team is now initiating a pilot study to investigate the feasibility of this CPR bundle, aiming to fill the prevailing evidence void in resuscitation research.

Keywords: Active compression/decompression CPR (ACE); Head Up CPR (HUP); Impedance Threshold Device (ITD); Neuroprotective CPR.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

References

    1. Hawkes C., Booth S., Ji C., et al. Epidemiology and outcomes from out- of-hospital cardiac arrests in England. Resuscitation. 2017;110:133–140. doi: 10.1016/j.resuscitation.2016.10.030. - DOI - PubMed
    1. Berdowski J., Berg R.A., Tijssen J.G.P., Koster R.W. Global incidences of out-of-hospital cardiac arrest and survival rates: Systematic review of 67 prospective studies. Resuscitation. 2010;81:1479–1487. doi: 10.1016/j.resuscitation.2010.08.006. - DOI - PubMed
    1. Moore J.C., Segal N., Lick M.C., et al. Head and thorax elevation during active compression decompression cardiopulmonary resuscitation with an impedance threshold device improves cerebral perfusion in a swine model of prolonged cardiac arrest. Resuscitation. 2017;121:195–200. - PubMed
    1. Moore J.C., Salverda B., Rojas-Salvador C., Lick M., Debaty G., Lurie G.K. Controlled sequential elevation of the head and thorax combined with active compression decompression cardiopulmonary resuscitation and an impedance threshold device improves neurological survival in a porcine model of cardiac arrest. Resuscitation. 2021;158:220–227. doi: 10.1016/J.RESUSCITATION.2020.09.030. - DOI - PMC - PubMed
    1. Moore J.C., Pepe P.E., Scheppke K.A., et al. Head and thorax elevation during cardiopulmonary resuscitation using circulatory adjuncts is associated with improved survival. Resuscitation. 2022;179:9–17. doi: 10.1016/j.resuscitation.2022.07.039. - DOI - PubMed

LinkOut - more resources