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Review
. 2023 Sep;47(5):605-614.
doi: 10.1016/j.jgr.2023.04.005. Epub 2023 May 4.

Effect of anti-skin disorders of ginsenosides- A Systematic Review

Lele Cong  1 , Jinli Ma  2 , Yundong Zhang  2 , Yifa Zhou  3 , Xianling Cong  4 , Miao Hao  5
Affiliations
Review

Effect of anti-skin disorders of ginsenosides- A Systematic Review

Lele Cong et al. J Ginseng Res. 2023 Sep.

Abstract

Ginsenosides are bioactive components of Panax ginseng with many functions such as anti-aging, anti-oxidation, anti-inflammatory, anti-fatigue, and anti-tumor. Ginsenosides are categorized into dammarane, oleanene, and ocotillol type tricyclic triterpenoids based on the aglycon structure. Based on the sugar moiety linked to C-3, C-20, and C-6, C-20, dammarane type was divided into protopanaxadiol (PPD) and protopanaxatriol (PPT). The effects of ginsenosides on skin disorders are noteworthy. They play anti-aging roles by enhancing immune function, resisting melanin formation, inhibiting oxidation, and elevating the concentration of collagen and hyaluronic acid. Thus, ginsenosides have previously been widely used to resist skin diseases and aging. This review details the role of ginsenosides in the anti-skin aging process from mechanisms and experimental research.

Keywords: anti-skin disorders; ginsenosides; protopanaxadiol type; protopanaxatriols type; skin aging.

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Conflict of interest statement

The author declares no conflicts of interest

Figures

Image 1
Graphical abstract
Fig. 1
Fig. 1
Schematic illustration of plausible biotransformation of PPD.
Fig. 2
Fig. 2
Schematic illustration of plausible biotransformation of PPT.
Fig. 3
Fig. 3
The functions of ginsenosides in human epidermal cells.
See this image and copyright information in PMC

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