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. 1986 Oct;20(2):105-9.
doi: 10.1002/jmv.1890200203.

Thermostabilization of Inoue-Melnick virus by salt

Thermostabilization of Inoue-Melnick virus by salt

Y Nishibe et al. J Med Virol. 1986 Oct.

Abstract

Inoue-Melnick virus (IMV) was stabilized to thermal inactivation at 50 degrees C by 1 M Na2SO4 but not by 1 M MgCl2, 1 M MgSO4, 2 M NaCl, and 2 M KCl. The latter salts enhanced the inactivation over that in distilled water. Na2SO4 stabilized IMV at 1 M concentration but enhanced inactivation at 0.1 M. Three types of IMV were stabilized by 1 M Na2SO4 at 50 degrees C to almost the same degree. The pattern of the thermostabilization of IMV by salts was similar to that of herpes simplex virus; however, the degree of its stabilization was lower with prolonged heating.

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