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Review
. 2023 Nov;9(6):2617-2624.
doi: 10.1002/vms3.1262. Epub 2023 Sep 18.

Research progress into the application of Mycobacterium phlei in veterinary medicine

Fan Li  1 , Xiang Li  2 , Meng-Lin Jiang  1 , Chun-Hua Wang  1 , Gao-Feng Liu  2 , Zi Yang  3 , Yong Wu  1
Affiliations
Review

Research progress into the application of Mycobacterium phlei in veterinary medicine

Fan Li et al. Vet Med Sci. 2023 Nov.

Abstract

Mycobacterium phlei is a gram-positive acid-fast mycobacterium from the family Mycobacteriaceae. It is a valuable resource for both natural drugs and microecological preparations. It has been widely used in the field of human medicine; however, in the field of animal husbandry and veterinary medicine, the research and application of M. phlei is still in the preliminary exploration stage. This study aims to summarize the research progress of M. phlei in the field of veterinary medicine and provide a valuable reference for future research. Key words, such as 'M. phlei', 'veterinary field', 'immune balancer', 'genome' and other relevant words to this study, were used to search through PubMed, Web of Science, SciELO, Science Direct and Google Scholar databases. The results showed that the culture conditions of M. phlei were relatively simple, but its bacterial composition and genome sequence were relatively complex, and various components in the cell wall may have immunoregulatory effects. Therefore, the inactivated preparation made from M. phlei can have various applications in the veterinary field, such as growth regulation, immune regulation, antitumour, anti-parasite and asthma treatment. The literature review indicates that M. phlei preparation is an efficient and convenient immune system balance agent. Despite the challenges associated with the use of M. phlei preparations, it has a strong potential for application in veterinary medicine.

Keywords: Mycobacterium phlei; genome characteristics; immune regulation; veterinary applications; veterinary medicine.

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Conflict of interest statement

All authors have no potential conflicts of interest.

Figures

FIGURE 1
FIGURE 1
PRISMA flow diagram.
FIGURE 2
FIGURE 2
Pedigree of mycobacteria.
See this image and copyright information in PMC

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