Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 Aug 17;15(8):e43665.
doi: 10.7759/cureus.43665. eCollection 2023 Aug.

Infarcts of a Cardioembolic Source Mimicking Lacunar Infarcts: Case Series With Clinical and Radiological Correlation

Affiliations
Case Reports

Infarcts of a Cardioembolic Source Mimicking Lacunar Infarcts: Case Series With Clinical and Radiological Correlation

Ahmed Harazeen et al. Cureus. .

Abstract

Lacunar strokes are the hallmark of cerebral small vessel disease. There are several well-established mechanisms for the pathogenesis of lacunar stroke, but the cardioembolic mechanism is not well-established. Three cases of acute ischemic stroke following elective cardiac and cerebral catheterization are reported. These cases had typical lacunar-looking infarcts on neuroimaging despite strong evidence of an embolic source with temporal correlation. Awareness of such findings and pathogenesis may help investigational workup and management of these patients.

Keywords: clinical correlation; embolic source; heart catheterization complications; lacunar infarcts; radiological correlation.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Axial MRI images
(A,B) DWI and ADC showing an acute small right posterior pontine infarct (white arrows) (C,D) DWI sequence and ADC showing an acute small infarct in the right cerebellar region (dashed arrows) DWI, diffusion-weighted image; ADC, apparent diffusion coefficient
Figure 2
Figure 2. Axial MRI images
(A,B) DWI and ADC showing an acute left pontine infarct (white arrow) (C) FLAIR sequence showing bilateral chronic infarcts in the right middle cerebral artery territory (right frontal operculum and right temporal lobe with a peripheral watershed infarct in the left parietal-occipital junction) (two dashed arrows) DWI, diffusion-weighted image; ADC, apparent diffusion coefficient
Figure 3
Figure 3. Axial MRI images
(A,B) DWI and corresponding ADC showing an acute right hemi-pons lesion (solid arrow) (C) FLAIR sequence showing multiple T2/FLAIR hyperintensities in a supratentorial deep, subcortical, and periventricular white matter consistent with chronic microvascular ischemic changes (dashed arrows) DWI, diffusion-weighted image; ADC, apparent diffusion coefficient

Similar articles

References

    1. Advances in understanding the pathophysiology of lacunar stroke: a review. Regenhardt RW, Das AS, Lo EH, Caplan LR. JAMA Neurol. 2018;75:1273–1281. - PMC - PubMed
    1. Pathophysiology of lacunar stroke: history’s mysteries and modern interpretations. Regenhardt RW, Das AS, Ohtomo R, Lo EH, Ayata C, Gurol ME. J Stroke Cerebrovasc Dis. 2019;28:2079–2097. - PMC - PubMed
    1. Atherosclerosis might be responsible for branch artery disease: evidence from white matter hyperintensity burden in acute isolated pontine infarction. Zhou L, Yao M, Peng B, Zhu Y, Ni J, Cui L. Front Neurol. 2018;9:840. - PMC - PubMed
    1. Risk factors for lacunar stroke: a case-control transesophageal echocardiographic study. Kazui S, Levi CR, Jones EF, Quang L, Calafiore P, Donnan GA. Neurology. 2000;54:1385–1387. - PubMed
    1. Lacunes: small, deep cerebral infarcts. Fisher CM. Neurology. 1965;15:774–784. - PubMed

Publication types

LinkOut - more resources