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Case Reports
. 2023 Aug 18;15(8):e43724.
doi: 10.7759/cureus.43724. eCollection 2023 Aug.

Xanthogranulomatous Oophoritis: A Rare Case Report

Pratibha Dawande  1 , Rashmi Wankhade  1 , Milind Pande  1
Affiliations
Case Reports

Xanthogranulomatous Oophoritis: A Rare Case Report

Pratibha Dawande et al. Cureus. .

Abstract

Xanthogranulomatous oophoritis is a rare, chronic and non-neoplastic condition in which a heavy foamy histiocyte inflammatory infiltrate admixed with neutrophils, plasma cells, multinucleated giant cells, fibroblasts and foci of necrosis causing extensive tissue damage and organ destruction. The gallbladder and kidney are just two examples of the different organs that exhibit histological changes resembling xanthogranulomatous alteration. The present case involved a 40-year-old female who presented with a tuboovarian mass and was ultimately diagnosed with xanthogranulomatous oophritis, despite initial clinicoradiological suspicions for malignancy. Xanthogranulomatous oophritis is a significant entity because, clinically and radiographically, it resembles tumours of the ovary and hinges on a careful histopathological analysis to establish a diagnosis.

Keywords: histiocytes; inflammation; macrophages; oophoritis; xanthogranulomatous.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Uterus with cervix with attached bilateral adnexa
Figure 2
Figure 2. Cut section of right ovary
Figure 3
Figure 3. Histopathological photomicrograph of xanthogranulomatous inflammation showing replacement of ovarian stroma by foamy macrophages and histiocytes (H and E, 10X)
White arrow showing foamy macrophage and black arrow showing histiocyte
Figure 4
Figure 4. Histopathological photomicrograph of xanthogranulomatous inflammation showing macrophages and histiocytes (H and E, 40X)
White arrows showing foamy macrophages and black arrows showing histiocytes
See this image and copyright information in PMC

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